Bemaj Pharmacy

Descriptions – Metoclopramide injection is a medicine that increases the movements or contractions of the stomach and intestines. It is used to help diagnose certain problems in the stomach or intestines. This medicine is also used to prevent the nausea and vomiting that may occur after surgery or after treatment with cancer medicines.

• Another medicine may be used with metoclopramide injection to prevent side effects that may occur when it is used with cancer medicines.
• Metoclopramide injection is also used to relieve symptoms (such as nausea, vomiting, heartburn, a feeling of fullness after meals, and loss of appetite) that are caused by a stomach problem called gastroparesis in patients with diabetes.

This medicine is available only with your doctor’s prescription. This product is available in the following dosage forms:

Solution

Which injection is given in stomach?

A subcutaneous (say ‘sub-kyoo-TAY-nee-us’) shot is an injection of medicine under the skin, but not in a muscle. Some medicines, such as insulin or the blood-thinner enoxaparin (Lovenox), are injected only under the skin. This type of shot is usually given in the belly or the thigh.

Is Buscopan injection safe?

Risk of adverse reactions – We have received 9 reports of patients who died after receiving hyoscine butylbromide injection (including a report from a coroner). In most of these cases, the fatal adverse reaction was reported as acute myocardial infarction or cardiac arrest.

How fast does Buscopan injection work?

2. Key facts –

Buscopan relieves the pain of stomach cramps by helping your gut to relax.The medicine works very quickly. Painful cramps should ease within 15 minutes.It’s unusual to have any side effects, but some people get a dry mouth, constipation and blurred vision.Buscopan comes on prescription and as 2 different products (Buscopan IBS Relief and Buscopan Cramps) that you can buy from a pharmacy or shop.If you’re self-treating with Buscopan, do not take it for longer than 2 weeks without checking with a doctor.

What triggers abdominal pain?

Stomach pain; Pain – abdomen; Belly ache; Abdominal cramps; Bellyache; Stomachache Abdominal pain is pain that you feel anywhere between your chest and groin. This is often referred to as the stomach region or belly. You know that awful feeling: you’re nauseous; your stomach feels like it’s tied in a knot, and you don’t even want to move. What does your pain mean? Well, let’s talk today about abdominal pain. So, what causes abdominal pain? Almost everyone has pain in their belly at one time or another.

Most of the time, a serious medical problem is not the cause, and how bad your pain is doesn’t always reflect the seriousness of the problem causing your pain. You may feel very bad pain if you are having gas or stomach cramps due to viral gastroenteritis, better known as a stomach virus. And some life-threatening conditions, such as colon cancer or a very early case of appendicitis, may cause only mild pain, or no pain at all.

The important thing to know about abdominal pain is when you need immediate medical care. Less serious causes of abdominal pain include constipation, irritable bowel syndrome, food allergies, lactose intolerance, food poisoning, and a stomach virus. Other, more serious, causes include appendicitis, an abdominal aortic aneurysm, a bowel blockage, cancer, and gastroesophageal reflux.

Sometimes, you may have abdominal pain from a problem that isn’t in your belly, like a heart attack, menstrual cramps, or pneumonia. So, what do you do about abdominal pain? Well, if you have mild abdominal pain, here are some helpful tips; Try sipping water or other clear fluids. Avoid solid food for the first few hours.

If you’ve been vomiting, wait 6 hours and then eat small amounts of mild foods like rice, applesauce, or crackers. If your pain is high in your abdomen and occurs after meals, antacids may help, especially if you are feeling heartburn or indigestion. You should seek medical attention if you have abdominal pain and are being treated for cancer, you can’t pass any stool, you’re vomiting blood, or you have chest, neck, or shoulder pain. There are three body views (front, back, and side) that can help you to identify a specific body area. The labels show areas of the body which are identified either by anatomical or by common names. For example, the back of the knee is called the “popliteal fossa,” while the “flank” is an area on the side of the body. The process of digesting food is accomplished by many organs in the body. Food is pushed by the esophagus into the stomach. The stomach mixes the food and begins the breakdown of proteins. The stomach propels the food then into the small intestine. The small intestine further digests food and begins the absorption of nutrients. Since the abdominal area contains many different organs it is divided in smaller areas. One division method, uses one median sagittal plane and one transverse plane that passes through the umbilicus at right angles. This method divides the abdomen into four quadrants. Medical personnel can easily refer to these quadrants when describing pain or injury regarding a victim. The appendix is a small finger-shaped tube that branches off the first part of the large intestine. The appendix can become inflamed or infected causing pain in the lower right part of the abdomen. Blood from the aorta reaches the kidneys so it can be filtered and cleaned. Among other functions, the kidneys remove toxins, metabolic waste, and excess ions from the blood which leaves the body in the form of urine. You know that awful feeling: you’re nauseous; your stomach feels like it’s tied in a knot, and you don’t even want to move.

What does your pain mean? Well, let’s talk today about abdominal pain. So, what causes abdominal pain? Almost everyone has pain in their belly at one time or another. Most of the time, a serious medical problem is not the cause, and how bad your pain is doesn’t always reflect the seriousness of the problem causing your pain.

You may feel very bad pain if you are having gas or stomach cramps due to viral gastroenteritis, better known as a stomach virus. And some life-threatening conditions, such as colon cancer or a very early case of appendicitis, may cause only mild pain, or no pain at all.

The important thing to know about abdominal pain is when you need immediate medical care. Less serious causes of abdominal pain include constipation, irritable bowel syndrome, food allergies, lactose intolerance, food poisoning, and a stomach virus. Other, more serious, causes include appendicitis, an abdominal aortic aneurysm, a bowel blockage, cancer, and gastroesophageal reflux.

Sometimes, you may have abdominal pain from a problem that isn’t in your belly, like a heart attack, menstrual cramps, or pneumonia. So, what do you do about abdominal pain? Well, if you have mild abdominal pain, here are some helpful tips; Try sipping water or other clear fluids.

Avoid solid food for the first few hours. If you’ve been vomiting, wait 6 hours and then eat small amounts of mild foods like rice, applesauce, or crackers. If your pain is high in your abdomen and occurs after meals, antacids may help, especially if you are feeling heartburn or indigestion. You should seek medical attention if you have abdominal pain and are being treated for cancer, you can’t pass any stool, you’re vomiting blood, or you have chest, neck, or shoulder pain.

Call your doctor if you have abdominal pain that lasts 1 week or longer, if your pain doesn’t improve in 24 to 48 hours, if bloating lasts more than 2 days, or if you have diarrhea for more than 5 days.

How long should abdominal pain last?

Common Causes of Stomach Pain – Harmless abdominal pain usually subsides or goes away within two hours. Some of the common causes for stomach pain are from:

Gas : Formed in the stomach and intestines as your body breaks down food, gas can cause general stomach pain and cramps. This often can be indicated by belching or flatulence. Bloating : Related to gas, bloating occurs when excess gas builds up in your digestive tract. Your stomach usually will feel full, and you may experience cramps. Constipation : This occurs when you are having difficulty making bowel movements. If you are having two or fewer bowel movements a week, constipation is the likely cause. In addition to feeling bloated and uncomfortable, you may experience cramping and pain in your rectum. Indigestion : This is typically experienced as an upset stomach, burning, or belly pain after eating. Stomach flu : Your stomach may hurt before each episode of vomiting or diarrhea,

Is Buscopan a pain killer?

Buscopan vs Drotaverine –

Buscopan	Drotaverine
Hyoscine is the active ingredient in Buscopan injection (also known as Scopolamine). It belongs to the antispasmodic drug class.	Drotaverine (also known as drotaverine) is an antispasmodic drug similar to papaverine in structure. Drotaverine is a phosphodiesterase 4 inhibitor that has no anticholinergic properties.
Buscopan is a drug that is used to relieve pain caused by smooth muscle spasms. It relieves stomach, intestine, bladder, and ureter cramps.	Drotaverine is an important treatment for twitches or spasms of the smooth muscles of the stomach and heart.
Some of the common and serious side effects of Buscopan are: Dizziness Dryness in mouth Pain in the injection site Constipation Difficulty in passing urine	Some of the common and serious side effects of Drotaverine are: Nausea Vomiting Dry mouth Change in pulse rate Dizziness

Who should not take Buscopan injection?

BUSCOPAN and BUSCOPAN FORTE are contraindicated in myasthenia gravis, mechanical stenosis in the gastrointestinal tract, paralytical or obstructive ileus, megacolon and in patients who have demonstrated prior hypersensitivity to hyoscine butylbromide or any other component of the products.

Is there Buscopan injection?

My Account Area – 1. Name of the medicinal product Buscopan Ampoules 20mg/ml solution for injection.2. Qualitative and quantitative composition Each 1ml ampoule contains 20 mg hyoscine butylbromide. For excipients, see 6.1.3. Pharmaceutical form Solution for injection A colourless or almost colourless, clear solution 4.

Clinical particulars 4.1 Therapeutic indications Buscopan Ampoules are indicated in acute spasm, as in renal or biliary colic, in radiology for differential diagnosis of obstruction and to reduce spasm and pain in pyelography, and in other diagnostic procedures where spasm may be a problem, e.g. gastro-duodenal endoscopy.4.2 Posology and method of administration Adults : One ampoule (20 mg) intramuscularly or intravenously, repeated after half an hour if necessary.

Intravenous injection should be performed ‘slowly’ (in rare cases a marked drop in blood pressure and even shock may be produced by Buscopan). When used in endoscopy this dose may need to be repeated more frequently. Maximum daily dose of 100mg. Special populations Elderly: No specific information on the use of this product in the elderly is available.

Clinical trials have included patients over 65 years and no adverse reactions specific to this age group have been reported. Paediatric population Not recommended for children. Buscopan Ampoules should not be taken on a continuous daily basis or for extended periods without investigating the cause of abdominal pain.

Diluent: Buscopan injection solution may be diluted with dextrose or with sodium chloride 0.9% injection solutions.4.3 Contraindications Buscopan Ampoules are contraindicated in patients with: – hypersensitivity to the active substance or to any of the excipients listed in section 6.1 – narrow angle glaucoma – hypertrophy of the prostate with urinary retention – mechanical stenosis in the gastrointestinal tract – paralytical or obstructive ileus – megacolon – tachycardia – myasthenia gravis Buscopan Ampoules should not be given by intramuscular injection to patients being treated with anticoagulant drugs since intramuscular haematoma may occur.4.4 Special warnings and precautions for use In case severe, unexplained abdominal pain persists or worsens, or occurs together with symptoms like fever, nausea, vomiting, changes in bowel movements, abdominal tenderness, decreased blood pressure, fainting, or blood in stool, appropriate diagnostic measures are needed to investigate the aetiology of the symptoms.

Buscopan Ampoules can cause tachycardia, hypotension and anaphylaxis, therefore use with caution in patients with cardiac conditions such as cardiac failure, coronary heart disease, cardiac arrhythmia or hypertension, and in cardiac surgery. Monitoring of these patients is advised. Emergency equipment and personnel trained in its use must be readily available.

Because of the possibility that anticholinergics may reduce sweating, Buscopan should be administered with caution to patients with pyrexia. Elevation of intraocular pressure may be produced by the administration of anticholinergic agents such as Buscopan in patients with undiagnosed and therefore untreated narrow angle glaucoma.

1. Therefore, patients should seek urgent ophthalmological advice in case they should develop a painful, red eye with loss of vision after the injection of Buscopan.
2. After parenteral administration of Buscopan, cases of anaphylaxis including episodes of shock have been observed.
3. As with all drugs causing such reactions, patients receiving Buscopan by injection should be kept under observation.4.5 Interaction with other medicinal products and other forms of interaction The anticholinergic effect of drugs such as tri- and tetracyclic antidepressants, antihistamines, quinidine, amantadine, antipsychotics (e.g.

phenothiazines, butyrophenones), disopyramide and other anticholinergics (e.g. tiotropium, ipratropium, atropine-like compounds) may be intensified by Buscopan. The tachycardic effects of beta-adrenergic agents may be enhanced by Buscopan. Concomitant treatment with dopamine antagonists such as metoclopramide may result in diminution of the effects of both drugs on the gastrointestinal tract.4.6 Fertility, pregnancy and lactation Pregnancy There are limited data from the use of hyoscine butylbromide in pregnant women.

Animal studies are insufficient with respect to reproductive toxicity (see section 5.3). As a precautionary measure Buscopan is not recommended during pregnancy. Lactation There is insufficient information on the excretion of hyoscine butylbromide and its metabolites in human milk. A risk to the breastfeeding child cannot be excluded.

Use of Buscopan during breastfeeding is not recommended. Fertility No studies on the effects on human fertility have been conducted.4.7 Effects on ability to drive and use machines No studies on the effects on the ability to drive and use machines have been performed.

However, patients should be advised that they may experience undesirable effects such as accommodation disorder or dizziness during treatment with Buscopan Ampoules. Therefore, caution should be recommended when driving a car or operating machinery. If patients experience accommodation disorder or dizziness, they should avoid potentially hazardous tasks such as driving or operating machinery.4.8 Undesirable effects Many of the listed undesirable effects can be assigned to the anticholinergic properties of BUSCOPAN.

Adverse events have been ranked under headings of frequency using the following convention:

Very common Common Uncommon Rare Very rare Not known

(≥ 1/10) (≥ 1/100 to < 1/10) (≥ 1/1,000 to <1/100) (≥ 1/10,000 to <1/1,000) (<1/10,000) (cannot be estimated from the available data)

Immune system disorders Not known*: anaphylactic shock including cases with fatal outcome, anaphylactic reactions, dyspnoea, and other hypersensitivity. Eye disorders Common: accommodation disorders Not known*: mydriasis, increased intraocular pressure Cardiac disorders Common: tachycardia Vascular disorders Common: dizziness Not known*: blood pressure decreased, flushing Gastrointestinal disorders Common: dry mouth Constipation Skin and subcutaneous tissue disorders Not known*: skin reactions (e.g.

urticaria, rash, erythema, pruritus), abnormal sweating Renal and urinary disorders Not known*: urinary retention Injection site pain, particularly after intramuscular use, occurs. Hyoscine butylbromide, the active ingredient of Buscopan, due to its chemical structure as a quaternary ammonium derivate, is not expected to enter the central nervous system.

Hyoscine butylbromide does not readily pass the blood-brain barrier. However, it cannot totally be ruled out that under certain circumstances psychiatric disorders (e.g. confusion) may also occur after administration of Buscopan. *This adverse reaction has been observed in post-marketing experience.

With 95% certainty, the frequency category is not greater than common, but might be lower. A precise frequency estimation is not possible as the adverse drug reaction did not occur in a clinical trial database of 185 patients. Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important.

It allows continued monitoring of the benefit / risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.4.9 Overdose Symptoms Serious signs of poisoning following acute overdosage have not been observed in man.

In the case of overdosage, anticholinergic symptoms such as urinary retention, dry mouth, reddening of the skin, tachycardia, inhibition of gastrointestinal motility and transient visual disturbances may occur, and Cheynes-Stokes respiration has been reported. Therapy Symptoms of Buscopan overdosage respond to parasympathomimetics.

For patients with glaucoma, pilocarpine should be given locally. Cardiovascular complications should be treated according to usual therapeutic principles. In case of respiratory paralysis: intubation, artificial respiration should be considered. Catheterisation may be required for urinary retention.

In addition, appropriate supportive measures should be used as required.5. Pharmacological properties 5.1 Pharmacodynamic properties Buscopan is an antispasmodic agent which relaxes smooth muscle of the organs of the abdominal and pelvic cavities. It is believed to act predominantly on the intramural parasympathetic ganglia of these organs.5.2 Pharmacokinetic properties Absorption and distribution After intravenous administration hyoscine butylbromide is rapidly distributed (t ½α = 4 min, t ½β = 29 min) into the tissues.

The volume of distribution (Vss) is 128 L (corresponding to approx.1.7 L/kg). Because of its high affinity for muscarinic receptors and nicotinic receptors, hyoscine butylbromide is mainly distributed on muscle cells of the abdominal and pelvic area as well as in the intramural ganglia of the abdominal organs.

1. Plasma protein binding (albumin) of hyoscine butylbromide is approximately 4.4%.
2. Animal studies demonstrate that hyoscine butylbromide does not pass the blood-brain barrier, but no clinical data to this effect is available.
3. Hyoscine butylbromide (1 mM) has been observed to interact with the choline transport (1.4 nM) in epithelial cells of human placenta in vitro,

Metabolism and elimination The main metabolic pathway is the hydrolytic cleavage of the ester bond. The half-life of the terminal elimination phase (t ½γ ) is approximately 5 hours. The total clearance is 1.2 L/min. Clinical studies with radiolabeled hyoscine butylbromide show that after intravenous injection 42 to 61% of the radioactive dose is excreted renally and 28.3 to 37% faecally.

The portion of unchanged active ingredient excreted in the urine is approximately 50%. The metabolites excreted via the renal route bind poorly to the muscarinic receptors and are therefore not considered to contribute to the effect of the hyoscine butylbromide. Paediatric population No particular pharmacokinetic studies concerning hyoscine butylbromide have been performed in children.5.3 Preclinical safety data In limited reproductive toxicity studies hyoscine butylbromide showed no evidence of teratogenicity in rats at 200 mg/kg in the diet or in rabbits at 200 mg/kg by oral gavage or 50 mg/kg by subcutaneous injection.

Fertility in the rat was not impaired at doses of up to 200 mg/kg in the diet.6. Pharmaceutical particulars 6.1 List of excipients Sodium Chloride Water for injections 6.2 Incompatibilities None known 6.3 Shelf life Unopened: 36 months Once opened, use immediately and discard any unused contents 6.4 Special precautions for storage Store below 30°C.

• Store in the outer carton.6.5 Nature and contents of container 1ml colourless glass (Ph. Eur.
• Type I) ampoules with coloured identification rings, marketed in cartons containing 10 ampoules.6.6 Special precautions for disposal and other handling For single use only.
• Any unused solution should be discarded.7.

Marketing authorisation holder Opella Healthcare UK Limited, trading as Sanofi 410 Thames Valley Park Drive Reading Berkshire RG6 1PT United Kingdom 8. Marketing authorisation number(s) PL 53886/0009 9. Date of first authorisation/renewal of the authorisation 23/06/2006 10.

What medicine is good for gas and stomach pain?

Over-the-counter remedies – The following products may reduce gas symptoms for some people:

Alpha-galactosidase (Beano, BeanAssist, others) helps break down carbohydrates in beans and other vegetables. You take the supplement just before eating a meal. Lactase supplements (Lactaid, Digest Dairy Plus, others) help you digest the sugar in dairy products (lactose). These reduce gas symptoms if you’re lactose intolerant. Talk to your doctor before using lactase supplements if you’re pregnant or breast-feeding. Simethicone (Gas-X, Mylanta Gas Minis, others) helps break up the bubbles in gas and may help gas pass through your digestive tract. There is little clinical evidence of its effectiveness in relieving gas symptoms. Activated charcoal (Actidose-Aqua, CharcoCaps, others) taken before and after a meal may reduce symptoms, but research has not shown a clear benefit. Also, it may interfere with your body’s ability to absorb medications. Charcoal may stain the inside of your mouth and your clothing.

Making lifestyle changes may help reduce or relieve excess gas and gas pain.

Try smaller portions. Many of the foods that can cause gas are part of a healthy diet. Try eating smaller portions of problem foods to see if your body can handle a smaller portion without creating excess gas. Eat slowly, chew your food thoroughly and don’t gulp. If you have a hard time slowing down, put down your fork between each bite. Avoid chewing gum, sucking on hard candies and drinking through a straw. These activities can cause you to swallow more air. Check your dentures. Poorly fitting dentures can cause you to swallow excess air when you eat and drink. See your dentist if they aren’t fitting correctly. Don’t smoke. Cigarette smoking can increase the amount of air you swallow. Talk to your doctor if you need help quitting. Exercise. Regular exercise reduces the risk of constipation, which can prevent the release of gas from your colon.

If the odor from passing gas concerns you, limiting foods high in sulfur-containing compounds — such as broccoli, Brussels sprouts, cabbage, cauliflower, beer and foods high in protein — may reduce distinctive odors. Pads, underwear and cushions containing charcoal also may help absorb unpleasant odors from passing gas.

What antibiotics treat abdominal pain?

Treatment for gastrointestinal infection includes taking antibiotics and staying hydrated. Common antibiotics used to treat gastrointestinal infection are penicillin, cephalosporin, antifolate / sulfa combinations, nitroimidazole, penem, glycopeptide, and monobactam antibiotics.

Is buscopan good for abdominal pain?

9. Common questions about Buscopan – How does Buscopan work? Buscopan relieves stomach cramps and period pains by helping your digestive system and bladder relax. It does this by reducing the wave-like contractions of the muscle in the walls of the stomach, bowel and bladder.

1. Buscopan helps to treat stomach cramps and period pains, but does not cure them.
2. When will I feel better? Buscopan tablets start to work within 15 minutes.
3. Talk to your pharmacist or doctor if your symptoms do not improve within 2 weeks.
4. Can I take Buscopan for a long time? Do not take Buscopan for longer than 2 weeks unless your doctor tells you to.

Talk to your doctor if your symptoms change, get worse or have not improved after 2 weeks. Your doctor will want to rule out an illness that may be causing your symptoms. Buscopan is safe to take for a long time (more than 3 months) as long as you get advice from your doctor, you take the recommended dose and you’re not having any side effects.

What’s the difference between Buscopan products? Buscopan Cramps and Buscopan IBS Relief are essentially identical. The tablets in each contain the same active ingredient (hyoscine butylbromide) and in the same strength (10mg). But the 2 products are marketed differently. Buscopan Cramps is targeted at stomach cramps.

It can also be used to relieve period pain and the cramping pains some people get with IBS. It’s only available from behind the pharmacy counter, and can be taken by adults and children over the age of 6 years. Buscopan IBS Relief is targeted at IBS that’s been confirmed by a doctor.

1. It’s for adults and children aged 12 years old and over.
2. The dose can be varied according to how severe your symptoms are.
3. It’s available from supermarkets as well as pharmacies.
4. Where can I buy Buscopan? Buscopan IBS Relief is available from most pharmacies and supermarkets.
5. Buscopan Cramps is only available from behind the pharmacy counter.

Can I take Buscopan with other IBS remedies? Do not take Buscopan at the same time as other irritable bowel syndrome (IBS) remedies – just take one type of remedy at a time. Can I take Buscopan with painkillers? Yes, you can take Buscopan at the same time as everyday painkillers like paracetamol or ibuprofen,

• Are there other IBS remedies? There are other IBS remedies, including peppermint oil (Colpermin) and mebeverine (Colofac).
• Peppermint oil and mebeverine are also antispasmodic remedies.
• They work in a similar way to Buscopan to relax stomach muscles and ease painful cramps.
• Both peppermint oil and mebeverine are available to buy from pharmacies.

Mebeverine is also available on prescription. Will it affect my fertility? There’s no evidence to suggest that taking Buscopan will reduce fertility in either men or women. If you’re trying to get pregnant and you take Buscopan regularly, speak to a pharmacist or your doctor.

They may want to review your treatment. Can I drive or ride a bike? Buscopan can give you blurred vision or make you dizzy. If this happens to you, do not drive, cycle or use machinery or tools until it’s worn off. It’s an offence to drive a car if your ability to drive safely is affected. It’s your responsibility to decide if it’s safe to drive.

If you’re in any doubt, do not drive. GOV.UK has more information on the law on drugs and driving, Talk to a doctor or pharmacist if you’re unsure whether it’s safe for you to drive while taking Buscopan. Can I drink alcohol with it? Yes, you can drink alcohol with Buscopan.

• Can lifestyle changes help? There are a number of lifestyle changes you can make to prevent or ease painful stomach cramps and irritable bowel syndrome (IBS),
• It can really help to understand which, if any, foods trigger your cramps and then reduce or remove them from your diet.
• Common triggers include caffeine, fizzy drinks and fried food.

It can also help to control your stress levels – for example, by doing breathing exercises or trying a relaxation therapy such as yoga, Pilates or meditation. Aim to exercise 3 times a week for at least 30 minutes. Regular activity is good for your digestive system.