Difference Between Infection And Inflammation Slideshare
Contents
What is the difference between an infection and an inflammation?
Inflammation is not a synonym for infection, even in cases where inflammation is caused by infection. Although infection is caused by a microorganism, inflammation is one of the responses of the organism to the pathogen.
Can there be inflammation without infection?
Measuring inflammation – When inflammation is present in the body, there will be higher levels of substances known as biomarkers. An example of a biomarker is C-reactive protein (CRP), If a doctor wants to test for inflammation, they may assess CRP levels.
Does inflammation fight infection?
Usually, inflammation enables our bodies to fight off bacteria, viruses and other toxins. But if that immune response continues unchecked, even after the threat has passed, the immune system can turn on healthy tissue.
How do you reduce inflammation from an infection?
Resting the swollen area and elevating it above the level of the heart (if possible) can also help. Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, reduce inflammation at the site of injury or infection and reduce the sensation of pain in the brain.
How long does inflammation last?
Inflammation is a process by which your body’s white blood cells and the things they make protect you from infection from outside invaders, such as bacteria and viruses. But in some diseases, like arthritis, your body’s defense system – your immune system – triggers inflammation when there are no invaders to fight off.
- In these autoimmune diseases, your immune system acts as if regular tissues are infected or somehow unusual, causing damage.
- Inflammation can be either short-lived ( acute ) or long-lasting ( chronic ).
- Acute inflammation goes away within hours or days.
- Chronic inflammation can last months or years, even after the first trigger is gone.
Conditions linked to chronic inflammation include:
Cancer Heart disease Diabetes Asthma Alzheimer’s disease
Some types of arthritis are the result of inflammation, such as:
Rheumatoid arthritis Psoriatic arthritis Gouty arthritis
Other painful conditions of the joints and musculoskeletal system that may not be related to inflammation include osteoarthritis, fibromyalgia, muscular low back pain, and muscular neck pain, Symptoms of inflammation include:
RednessA swollen joint that may be warm to the touch Joint pain Joint stiffness A joint that doesn’t work as well as it should
Often, you’ll have only a few of these symptoms. Inflammation may also cause flu-like symptoms including:
Fever Chills Fatigue /loss of energy Headaches Loss of appetiteMuscle stiffness
When inflammation happens, chemicals from your body’s white blood cells enter your blood or tissues to protect your body from invaders. This raises the blood flow to the area of injury or infection. It can cause redness and warmth. Some of the chemicals cause fluid to leak into your tissues, resulting in swelling. Your doctor will ask about your medical history and do a physical exam, focusing on:
The pattern of painful joints and whether there are signs of inflammationWhether your joints are stiff in the morningAny other symptoms
They’ll also look at the results of X-rays and blood tests for biomarkers such as:
C-reactive protein (CRP)Erythrocyte sedimentation rate (ESR)
Inflammation can affect your organs as part of an autoimmune disorder. The symptoms depend on which organs are affected. For example:
Inflammation of your heart ( myocarditis ) may cause shortness of breath or fluid buildup.Inflammation of the small tubes that take air to your lungs may cause shortness of breath.Inflammation of your kidneys (nephritis) may cause high blood pressure or kidney failure.
You might not have pain with an inflammatory disease, because many organs don’t have many pain-sensitive nerves. Treatment for inflammatory diseases may include medications, rest, exercise, and surgery to correct joint damage, Your treatment plan will depend on several things, including your type of disease, your age, the medications you’re taking, your overall health, and how severe the symptoms are.
Correct, control, or slow down the disease processAvoid or change activities that aggravate painEase pain through pain medications and anti-inflammatory drugsKeep joint movement and muscle strength through physical therapy Lower stress on joints by using braces, splints, or canes as needed
Medications Many drugs can ease pain, swelling and inflammation. They may also prevent or slow inflammatory disease. Doctors often prescribe more than one. The medications include:
Nonsteroidal anti-inflammatory drugs ( NSAIDs, such as aspirin, ibuprofen, or naproxen )Corticosteroids (such as prednisone)Antimalarial medications (such as hydroxychloroquine )Other medicines known as disease-modifying antirheumatic drugs (DMARDs), including azathioprine, cyclophosphamide, leflunomide, methotrexate, and sulfasalazine Biologic drugs such as abatacept, adalimumab, certolizumab, etanercept, infliximab, golimumab, rituximab, and tocilizumab
Some of these are also used to treat conditions such as cancer or inflammatory bowel disease, or to prevent organ rejection after a transplant. But when ” chemotherapy ” types of medications (such as methotrexate or cyclophosphamide) are used to treat inflammatory diseases, they tend to have lower doses and less risk of side effects than when they’re prescribed for cancer treatment,
Quit smoking,Limit how much alcohol you drink.Keep a healthy weight, Manage stress,Get regular physical activity,Try supplements such as omega-3 fatty acids, white willow bark, curcumin, green tea, or capsaicin, Magnesium and vitamins B6, C, D, and E also have some anti-inflammatory effects. Talk with your doctor before starting any supplement.
Surgery You may need surgery if inflammation has severely damaged your joints. Common procedures include:
Arthroscopy. Your doctor makes a few small cuts around the affected joint. They insert thin instruments to fix tears, repair damaged tissue, or take out bits of cartilage or bone, Osteotomy. Your doctor takes out part of the bone near a damaged joint. Synovectomy. All or part of the lining of the joint (called the synovium) is removed if it’s inflamed or has grown too much. Arthrodesis, Pins or plates can permanently fuse bones together. Joint replacement. Your doctor replaces a damaged joint with an artificial one made of metal, plastic, or ceramic.
The things you eat and drink can also play a role in inflammation. For an anti-inflammatory diet, include foods like:
Tomatoes Olive oilLeafy green vegetables (spinach, collards)Nuts (almonds, walnuts)Fatty fish ( salmon, tuna, sardines)Fruits (berries, oranges )
These things can trigger inflammation, so avoid them as much as you can:
Refined carbohydrates (white bread )Fried foods (French fries)Sugary drinks (soda)Red and processed meats (beef, hot dogs)Margarine, shortening, and lard
What diseases cause inflammation?
Acute and chronic – There are two types of inflammation: acute and chronic. People are most familiar with acute inflammation. This is the redness, warmth, swelling, and pain around tissues and joints that occurs in response to an injury, like when you cut yourself.
When the body is injured, your immune system releases white blood cells to surround and protect the area. “Acute inflammation is how your body fights infections and helps speed up the healing process,” says Dr. Shmerling. “In this way, inflammation is good because it protects the body.” This process works the same if you have a virus like a cold or the flu.
In contrast, when inflammation gets turned up too high and lingers for a long time, and the immune system continues to pump out white blood cells and chemical messengers that prolong the process, that’s known as chronic inflammation. “From the body’s perspective, it’s under consistent attack, so the immune system keeps fighting indefinitely,” says Dr.
- Shmerling.
- When this happens, white blood cells may end up attacking nearby healthy tissues and organs.
- For example, if you are overweight and have more visceral fat cells — the deep type of fat that surrounds your organs — the immune system may see those cells as a threat and attack them with white blood cells.
The longer you are overweight, the longer your body can remain in a state of inflammation. Research has shown that chronic inflammation is associated with heart disease, diabetes, cancer, arthritis, and bowel diseases like Crohn’s disease and ulcerative colitis.
What does inflammation mean infection?
(IN-fluh-MAY-shun) A normal part of the body’s response to injury or infection. Inflammation occurs when the body releases chemicals that trigger an immune response to fight off infection or heal damaged tissue. Once the injury or infection is healed, the inflammatory process ends.