Joine Cure Capsule

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Joine Cure Capsule

What is the use of joint care capsule?

Herbal Vibe Joint Care Capsule has 100% ayurvedic formulation of 6 powerful herbal ingredients that help in stimulating blood circulation. It also helps in reducing stiffness and swelling.It provides effective relief from severe joint pain. Helps in improving overall health and wellness. Key Ingredients:

Ashwagandha extract

Saunth extract

Key Benefits:

Herbal formulation meant to cure problems like arthritis, back pain,etc.

Helps very much for muscular pain

Helps in stimulation of blood circulation

Formulated with natural ingredients

Directions for use:

Take 1 capsule twice a day with lukewarm water after meal or as directed by the physician

Safety Information:

Read the label carefully before use

Keep out of the reach of children

Use under medical supervision

Do not exceed the recommended dosage

Store in a cool and dry place

What is Joiflex capsules used for?

How Jointflex Tablet works – Jointflex Tablet is a proteoglycan synthesis stimulator that relieves osteoarthritis symptoms. It helps in the formation of cartilage (the soft tissue that cushions the joints) and keeps the joints lubricated for better movement and flexibility.

Is it safe to take joint supplements?

Research is mixed on whether these supplements help with OA pain and stiffness, but they are safe to try. Glucosamine and chondroitin are popular supplements used to treat osteoarthritis (OA), According to one estimate from the National Institutes of Health, 6.5 million adults, or 2.6% of the population, has used one or both of these products.

Although studies on glucosamine and chondroitin have been mixed, some evidence suggests they may help relieve OA joint pain and stiffness. What Are Glucosamine and Chondroitin? Glucosamine and chondroitin are natural compounds found in healthy cartilage — the connective tissue that cushions joints. Supplements are manufactured from the cartilage of animals such as cows, pigs or shellfish, or are made in a lab.

Glucosamine is sold in different forms, including glucosamine sulfate and glucosamine hydrochloride. You can buy glucosamine and chondroitin individually, but most often they’re sold together in a single supplement. In many European countries, these supplements are a prescribed treatment for OA.

In the U.S., the recommendations on glucosamine and chondroitin are more moderate, due to the mixed results of studies. How Do They Work? In OA, the gradual degeneration of cartilage leads to pain, swelling, and other symptoms. Glucosamine and chondroitin have anti-inflammatory properties. “They also have some cartilage-protecting effects through a variety of different mechanisms,” says Chris D’Adamo, PhD, director of Research & Education at the University of Maryland School of Medicine Center for Integrative Medicine.

Glucosamine and chondroitin protect cells called chondrocytes, which help maintain cartilage structure. In theory, these supplements have the potential to slow cartilage deterioration in the joints, and to reduce pain in the process. The Evidence The most comprehensive long-term study — the Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT) — compared the combination of glucosamine hydrochloride and chondroitin, both supplements individually, celecoxib ( Celebrex ) and a placebo (inactive pill) in nearly 1,600 people with knee osteoarthritis.

  • The first phase of GAIT, published in 2006, found that the combination of glucosamine and chondroitin sulfate didn’t offer significant relief to participants in general, but it did help a small subgroup of those with moderate-to-severe knee pain.
  • In follow-up results of the study released in 2010, these supplements improved pain and function, although no better than a placebo or the NSAID drug celecoxib.

Since the GAIT trial came out, a few large studies have shown more positive results, says D’Adamo. “If you look at the totality of the evidence for glucosamine and chondroitin for osteoarthritis of the knee, it’s very strong.” A 2016 multinational study called the MOVES trial found the combination of glucosamine and chondroitin as effective at relieving knee OA pain and swelling as celecoxib, without the side effects.

  1. The authors say these supplements could be a good alternative for people who aren’t good candidates for NSAIDs because they have cardiovascular or GI conditions.
  2. And another 2015 study found the combination helped reduce joint space narrowing — a sign of cartilage degeneration.
  3. Reviews of studies have yielded mixed results about these supplements.

Some found the supplements offered pain relief and function compared to placebo, while others didn’t. The difference in outcomes may be due to the variety of supplement types and doses researchers used. Which Form Is Best? Studies have also differed on which of these supplements offers the greatest benefit for OA.

Some find chondroitin to be superior, others favor glucosamine, while still others prefer a combination of the two. “Evidence would favor the two,” D’Adamo says. “They’re typically bundled that way when you buy them.” The ideal form of glucosamine has also caused dissent in the research community. Some studies show an advantage to glucosamine sulfate; others to glucosamine hydrochloride.

One study that compared the two glucosamine forms head to head found no real difference between them. “There are some studies that show improved joint flexibility and range of motion with glucosamine sulfate,” says Farshad Fani Marvasti, MD, MPH, director of Public Health, Prevention, and Health Promotion at The University of Arizona.

  1. That’s the one I would take if you’re going to take it for joint stiffness.” Mayo Clinic researchers agree, saying that evidence supports trying glucosamine sulfate — not hydrochloride — with or without chondroitin sulfate for knee OA.
  2. Are They Safe? Glucosamine and chondroitin are considered safe, with no serious side effects reported in studies.

However, these supplements can interact with blood thinners like warfarin ( Coumadin ). They might also affect blood sugar levels, and one small study found they raise eye pressure, which could increase the risk for glaucoma. If you have diabetes or glaucoma, you may need to avoid these supplements, or have your doctor monitor your blood sugar levels and eye pressure more closely while you take them.

  1. The Bottom Line In 2019 OA treatment guidelines, the Arthritis Foundation and American College of Rheumatology give a conditional recommendation of chondroitin sulfate for hand OA.
  2. The National Center for Complementary and Integrative Health (NCCIH) says the evidence on glucosamine for OA pain is unclear, and chondroitin isn’t helpful, but that these supplements haven’t been shown to be harmful.
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That means that there isn’t strong evidence that benefits outweigh risk, but the supplement could be helpful for people with OA. If you do want to try glucosamine and/or chondroitin, check with your doctor and pharmacist first to make sure it’s safe for you, and that it won’t interact with any other drugs you take.

What are the side effects of joint flex?

About JointFlex Products – Common Side Effects of JointFlex are Nausea, Heartburn, Upset stomach. Glucosamine is a proteoglycan synthesis stimulator which relieves osteoarthritis symptoms. It helps in the formation of cartilage (the soft tissue that cushions the joints) and keep the joints lubricated for better movement and flexibility. Patient Concerns about JointFlex Products

Who Cannot take glucosamine?

Temporomandibular joint disorders – Some sources claim that glucosamine is an effective therapy for temporomandibular joint (TMJ) disorders. These are health issues related to your jaw — like jaw pain and locking of the jaw joint. However, research to support this claim remains insufficient.

One small study showed a significant reduction in pain and inflammatory markers as well as increased jaw mobility in participants who received a combined supplement of glucosamine sulfate and chondroitin ( 23 ). Another study showed a significant improvement in maximum mouth opening and pain reduction — demonstrated by reduced inflammatory markers — after taking 1.5 grams of glucosamine and 1.2 grams of chondroitin sulfate daily for 8 weeks ( 24 ).

Although these study results are promising, they don’t offer enough data to support any definitive conclusions. As such, more research is needed on the topic. Summary While glucosamine is often regarded as an effective treatment for a wide variety of conditions, there is no conclusive data on its impact.

  1. Ultimately, more research is needed.
  2. Though broad claims are made about glucosamine’s positive effects on many conditions, available research only supports its use for a narrow range of them.
  3. Currently, the strongest evidence supports glucosamine sulfate use for the long-term treatment of OA symptoms.

But even then, evidence remains inconclusive ( 25, 26, 27 ). Besides this, glucosamine is less likely to be an effective treatment for other diseases or inflammatory conditions. If you’re still considering using glucosamine, consider the quality of the supplement you choose.

  • It’s best to check for third-party certification to ensure you’re getting exactly what you’re paying for.
  • Manufacturers willing to have their products tested for purity tend to have higher standards.
  • ConsumerLab, NSF International, and US Pharmacopeia (USP) are a few independent companies that provide certification services.

If you see one of their logos on your supplement, it’s more likely to be of good quality. Summary Most research supports the use of glucosamine-sulfate solely for managing OA symptoms, but even then, evidence remains inconclusive. Based on available studies, the supplement is less likely to be effective for any other conditions.

glucosamine sulfateglucosamine hydrochlorideN-Acetyl glucosamine

There appear to be no differences between their anti-inflammatory effects. Most studies that have found glucosamine effective for improving osteoarthritis symptoms used the sulfate version ( 28 ). Glucosamine sulfate is commonly sold in combination with chondroitin sulfate.

nausea and vomitingdiarrheaheartburnabdominal pain

You should not take glucosamine if you’re pregnant or breastfeeding due to a lack of evidence on its safety. Also, know that glucosamine may have a small hypoglycemic effect in people with type 2 diabetes, though the risk is relatively low. If you have diabetes or are taking diabetes medications, talk with your doctor before taking glucosamine ( 6 ).

  1. Glucosamine may also increase glaucoma risk.
  2. Therefore, it shouldn’t be taken by those at risk of developing glaucoma, including those with a family history of glaucoma, people ages 60 or older, and those who have diabetes, heart disease, or high blood pressure ( 31 ).
  3. Summary Glucosamine is likely safe for most people, although mild gastrointestinal upset has been reported in some individuals.

Avoid these supplements if you are at risk for glaucoma or if you’re pregnant or breastfeeding. Glucosamine exists naturally within your body and plays a vital role in the development and maintenance of healthy joints. Glucosamine supplements are commonly taken to treat various joint, bone, and inflammatory diseases like IBD, IC, and TMJ.

What joint supplements should I avoid?

Many people take vitamins and supplements to help ease joint pain and arthritis. How effective are these supplements? Here are tips to help you choose the right supplements for your joints. Arthritis Joint Pain: Supplements and Herbs Some people use supplements to try to help manage joint pain from arthritis.

Glucosamine, chondroitin, omega-3, and green tea are just a few of them. Glucosamine Glucosamine has been touted as an anti-inflammatory that helps keep the cartilage in joints healthy. Studies have shown some benefit for joint pain, but they are not conclusive. Natural glucosamine levels drop as people age.

Chondroitin Chondroitin is often used with glucosamine as an osteoarthritis treatment. Chondroitin, however, has not been shown to help with joint pain. The research into the effectiveness of glucosamine and chondroitin for arthritis symptoms is mixed.

  • Doctors do not recommend these supplements but are not opposed to their use if a patient gets relief from using them.
  • Doctors recommend against using glucosamine hydrochloride.
  • Omega-3 Fatty Acids Omega-3 fatty acids, found in fish oil and other foods, encourage the body to produce chemicals that help control inflammation.

This supplement may help ease stiffness caused by inflammation in people with rheumatoid arthritis, but more research is needed. Curcumin (active ingredient of turmeric) and/or Boswellia serrata Curcumin (active ingredient of turmeric) and/or Boswellia serrata provides relief for people with osteoarthritis of the knee.

  • They have anti-inflammatory properties.
  • Green tea Green tea contains compounds that have powerful antioxidant and anti-inflammatory properties that may be helpful in combating joint pain.
  • Vitamin D Vitamin D is important for keeping bones strong and preventing injuries from falls.
  • Research shows that people with low levels of vitamin D may have more joint pain.

Information About Vitamins and Supplements Do you know how to evaluate vitamins and supplements ? There are so many vitamins, supplements, and herbal extracts on the shelves. Use these tips to find out which ones may be right for you. Safe Upper Limits for Vitamins and Minerals When it comes to vitamins and minerals, how much should you take ? Find out the safe upper limits for the vitamins you take, as well as the recommended daily allowance you may need.

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Is glucosamine bad for kidneys?

5. Glucosamine Side Effects – The side effects of glucosamine have been noted after a long time of users taking the wrong supplement. Most glucosamine supplements are generally well tolerated, but adverse reactions have been reported in patients who abuse glucosamine.

  • The most common reactions include bowel irritation, nausea, vomiting, heartburn, diarrhea, and constipation.
  • In addition, some patients also found glucosamine to cause sensitization reactions in the epigastrium.
  • This condition usually occurs when glucosamine is taken before meals.
  • In addition, the improper use of Glucosamine also causes other serious reactions, affecting the digestive system such as bloating, abdominal distension, loose stools, tingling abdominal pain.

Patients treated with glucosamine for long-term pain relief also noticed symptoms such as difficulty sleeping, dizziness, flaky, dry skin and nail structure,. Some users commented Glucosamine causes temporary high blood pressure that makes them anxious.

  1. In addition, some reports related to glucosamine in cases of users experiencing skin reactions (itching, urticaria).
  2. People using glucosamine who have an allergic reaction or anaphylaxis will experience chest tightness and cyanosis, but these are very rare.
  3. Notes when using Glucosamine supplements As recommended by doctors, only use glucosamine if you are having problems with bones and joints.

In order for Glucosamine to be well absorbed, users need to know how to use it correctly, so that the best benefits of this preparation can be maximized and no side effects arise. The following are the notes when you use glucosamine: Normally in 1 Glucosamine tablet there is about 1500 mg of pure glucose, for good decomposition, you should take glucosamine with meals or right after eating.

When taking Glucosamine, you drink it with lots of water, use filtered or warm water instead of soft drinks, fruit juices. Build a nutritious diet, supplement with healthy foods and drinks, copper. should limit unhealthy foods and drinks such as alcohol and tobacco. Experts recommend that users should maintain a dose of 1,500mg of glucosamine / day for the first 1-2 months, and gradually reduce the dose within 3-6 months.

Using different types of glucosamine at the same time with different doses may increase overdose reactions, such as hyperglycemia, or unstable blood pressure. Depending on the location of each person, the ability to receive Glucosamine will be different, but users should adhere to the treatment time and have an appropriate dose.

  • After each course of combined therapy using glucosamine and other medical methods, a general examination is required to evaluate the effectiveness to continue the course or not.
  • According to many studies, glucosamine is classified as a slow-acting drug.
  • Glucosamine has the main effect on arthritis symptoms, which may develop after 2-3 months of continuous use.

Reasonable exercise is an important condition for a healthy body. Taking glucosamine is harmful to the kidneys no longer depending on the user’s usage. However, to date there have been long-term studies showing changes in renal function with long-term glucosamine abuse.

Therefore, users should consult their treating doctor and carefully read the drug information, do not use the drug in excess or prolong the treatment time, which will cause difficult-to-control side effects. Please dial for more information or register for an appointment, Download to make appointments faster and to manage your bookings easily.

XEM THÊM: : Is taking glucosamine bad for the kidneys?

How long can you take joint supplements?

When taken by mouth: Glucosamine sulfate is likely safe in most adults when used for up to 3 years. Glucosamine hydrochloride is possibly safe for most adults when used for up to 2 years. N-acetyl glucosamine is also possibly safe when used for up to 6 months.

Do joints hurt more after taking glucosamine?

A landmark study of glucosamine and chondroitin – A of glucosamine and chondroitin enrolled 164 patients with knee pain due to and gave half of them a combination of glucosamine and chondroitin; the other half received an identical placebo pill. The study was stopped early for an unusual reason: those taking the supplement actually reported worse symptoms than those taking a placebo.

This raises the possibility that taking glucosamine and chondroitin might make your joints feel worse than doing nothing. Did this study or subsequent research spell the end of people taking glucosamine, chondroitin, or both? Not at all! While the evidence of benefit is certainly not compelling, some studies have found that these supplements provide modest benefit, and people who feel it is helping them may not care so much about individual studies anyway.

Even if a treatment is not effective on average, there may be folks who, for whatever reason, get real relief from it. Finally, people are taking glucosamine and/or chondroitin for a number of reasons and conditions other than osteoarthritis of the hip or knee, so these studies may not apply to them.

What are the long term side effects of glucosamine?

Glucosamine sulfate is a natural sugar found in and around the fluid and tissues that cushion your joints. This tissue is called cartilage. Glucosamine is also found in the hard covering of shellfish. Glucosamine sulfate supplements are often made using shellfish.

  1. The substance can also be made in a laboratory.
  2. Glucosamine sulfate is a widely used supplement that may help ease pain in people with osteoarthritis,
  3. Osteoarthritis happens when cartilage breaks down.
  4. This can cause joint pain,
  5. Millions of people in the U.S.
  6. Have osteoarthritis,
  7. Scientists have been studying glucosamine sulfate alone, and together with another supplement called chondroitin, for many years.

Research results have been conflicting. Some studies show the supplement reduces knee pain in people with moderate-to-severe osteoarthritis. However, it doesn’t seem to work as well in people who:

Have mild knee painHave had the condition for a long timeAre overweight

The supplement seems to reduce pain as much as ibuprofen, But it doesn’t work as fast. It can take four to eight weeks for glucosamine sulfate to ease pain. Some studies show that glucosamine sulfate may also work for:

Osteoarthritis of the hip or spineArthritis of the temporomandibular joint ( TMJ ) in the jaw

A study in men also suggests that glucosamine sulfate may help a person bend and flex the knee better after a sudden knee injury, Glucosamine may also slow the progression of osteoarthritis. but the studies are mixed. Optimal doses of glucosamine sulfate have not been established.

Supplement ingredients and quality may vary widely from maker to maker. This makes it hard to establish a standard dose. The dose used in many studies to treat knee osteoarthritis was 500 milligrams, taken three times a day. There are different forms of glucosamine. Check the supplement’s ingredients. Some may contain glucosamine sulfate.

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Other supplements may have glucosamine hydrochloride or another type. Most studies have used glucosamine sulfate. Glucosamine is sometimes found in skin creams used to treat arthritis pain. There is no proof that glucosamine can move through your skin. Scientists think the pain relief may be due to other ingredients in the cream.

Studies done in a laboratory dish hint that glucosamine sulfate may help fight HIV, the virus that causes AIDS. Much more comprehensive research is needed before scientists can say whether or not this supplement could be helpful for those with the virus. You cannot get glucosamine sulfate from foods. It is a natural chemical found in the human body.

It is also found in the shells of shellfish. Glucosamine appears to be safe, even when taken for a few years. Side effects may include:

Constipation Diarrhea Drowsiness Headache Heartburn Nausea Rash

Glucosamine may affect blood sugar and insulin levels. However, studies are mixed. Talk to your doctor before taking this supplement if you have diabetes or insulin resistance, Animal studies show that glucosamine may further increase LDL “bad” cholesterol levels if you eat a lot of fatty foods.

acetaminophen ( Tylenol )Certain chemotherapy drugs, including doxorubicin, etoposide, and teniposide ( Vumon ) Diabetes drugs, including glimepiride ( Amaryl ), glyburide, insulin, pioglitazone ( Actos ), and rosiglitazone ( Avandia )

Talk to your doctor before using this supplement if you are allergic to shellfish, Always tell your doctor about any supplements you are taking, including natural ones and those bought without a prescription. That way, your doctor can check on any potential side effects or interactions with any medications,

Can too much glucosamine be harmful?

Some glucosamine products also contain manganese. Taking too much of this combination can cause a manganese overdose. Do not take more than directed on the medicine label.

Are the capsules in pills safe?

Gelatin-based capsules are widely available in the market as they are cheap to produce. According to FDA, the intake of gelatin in food is safe although there is no standard dosage. However, capsules made from gelatin carry some side effects too.

How long does it take for capsules to start working?

What happens to drugs in the body? – When you take a drug, it is absorbed into the blood and distributed round the body. The drug reaches a peak level. Soon after this, the drug level falls steadily as its is eliminated from the body. How a drug is absorbed by your body into the blood depends on the way it is taken:

A pill is usually absorbed into the blood through the stomach walls after it is swallowed – these can become active in a few minutes but usually take an hour or two to reach the highest concentration in the blood. IV drugs are injected directly into the blood work much faster – sometimes in seconds or minutes.

However a drug is taken, it will reach a peak level and then these levels will go down as the body breaks down the active ingredients, usually as the circulating blood is filtered by the liver or kidneys. This basic process happens with every drug – alcohol, nicotine, aspirin, HIV drugs Drugs are always absorbed more quickly than the body can break them down, so the highest concentration is reached relatively quickly, and then it takes longer to leave the body.

Are capsules or tablets better?

Fast: Capsules tend to act faster than tablets. No taste: Capsule shells don’t usually have the same medicinal taste as tablets. Better absorption: Capsules can have a higher bioavailability, meaning more of the medication enters your bloodstream, which makes them slightly more effective than tablets on average.

Do joint care pills work?

Skip to content We would like to say, “Yes, the supplements always work and relieve pain.” But the best we can say is, “They work for some people, some of the time.” Major studies show they may work slightly better than placebo for people who have knee pain caused by osteoarthritis.

How long can you take joint supplements?

When taken by mouth: Glucosamine sulfate is likely safe in most adults when used for up to 3 years. Glucosamine hydrochloride is possibly safe for most adults when used for up to 2 years. N-acetyl glucosamine is also possibly safe when used for up to 6 months.

What are the benefits of glucosamine capsules?

Overview – Glucosamine is a natural compound found in cartilage — the tough tissue that cushions joints. In supplement form, glucosamine is harvested from shells of shellfish or made in a lab. There are several forms of glucosamine, including glucosamine sulfate, glucosamine hydrochloride and N-acetyl glucosamine.

How often should I take joint supplements?

If you’re looking for a supplement that may ease your joint pain, glucosamine might be worth a try. Some studies show it gives relief for mild to moderate knee osteoarthritis, and it may work for other joints, too. Glucosamine is a natural chemical compound in your body.

But it also comes in the form of a supplement. There are two main types: hydrochloride and sulfate. The glucosamine in your body helps keep up the health of your cartilage – the rubbery tissue that cushions bones at your joints. But as you get older, your levels of this compound begin to drop, which leads to the gradual breakdown of the joint.

There’s some evidence that glucosamine sulfate supplements help counteract this effect, although experts aren’t sure how. Some people have also used glucosamine to try to treat rheumatoid arthritis and other conditions, such as inflammatory bowel disease, asthma, allergies, chronic venous insufficiency, sports injuries, temporomandibular joint problems ( TMJ ), and long-term low back pain.

So far, though, there’s not much scientific evidence that it works for those problems. In most studies on treating osteoarthritis, the typical dose was 500 milligrams of glucosamine sulfate, three times a day. Ask your doctor what they recommend for you. Some experts suggest you take it with meals to prevent an upset stomach.

Although glucosamine sulfate supplements are often manufactured from the shells of shellfish, there aren’t any natural food sources of glucosamine. On the whole, glucosamine seems to be a fairly safe supplement. Side effects are generally mild. You’re more likely to get them if you take high doses.

Upset stomach Heartburn Drowsiness Headache

Risks. If you have a shellfish allergy, be cautious about using glucosamine because you could have a reaction. Also, check with your doctor before taking supplements if you have diabetes, kidney disease, heart disease, bleeding disorders, or high blood pressure,