Pain No One Can Understand Me
- 0.1 What is emotional loneliness?
- 0.2 Is it normal for no one to talk to you?
- 1 What is the most painful mental pain?
- 2 What is the most painful emotion?
- 3 Who has a higher pain tolerance?
- 4 Why can’t I cry anymore?
Why am I in so much pain emotionally?
What is Emotional Pain? – When you experience difficult emotions, you experience emotional pain. A person may experience emotional distress due to various factors, including grief, loss, trauma, stress, or toxic relationships. These experiences leave an imprint on the mind and body.
- Even though these experiences can empower you and teach you valuable life lessons, suppressing emotional pain can negatively affect your health, success, and happiness.
- The actions of others can sometimes cause emotional pain.
- Depression or could also be the reason, in other cases.
- A person’s thoughts can often trigger emotions.
Therefore, mental and emotional pain are interconnected. Having anxiety, for example, affects how you handle emotions and may prevent you from going about your usual routines. A traumatic event also causes emotional pain for some people, such as losing a loved one.
Fatigue Less time with family and friends Anger issues Having trouble eating No motivation to do tasks Feeling helpless, guilt-ridden, or hopeless
Regardless of the cause, emotional pain affects many different aspects of a person’s life. It is essential to learn how to deal with it in healthy ways. Using suitable coping mechanisms can help you with healing emotional pain and overcoming it.
Why can’t I feel pain anymore?
Loss of sensation means that you can’t feel pain, heat, or cold. This can happen in one or more parts of your body. Loss of sensation can be caused by a complication of diabetes called peripheral neuropathy. This is a type of nerve damage. Other conditions that may cause you to lose feeling are stroke, spinal cord injury, tumors, and infections.
What is emotional loneliness?
Emotional loneliness – ‘ the absence of meaningful relationships ‘ Social loneliness – a ‘perceived deficit in the quality of social connections’ Existential loneliness – a ‘feeling of fundamental separateness from others and the wider world’
Is it normal for no one to talk to you?
A Word From Verywell – It’s not uncommon to feel like you have no one to talk to. In fact, everyone feels that way at least once in their life. You don’t have to be alone to feel that way either. You could feel alone and isolated at a party, at work, in your home, or even while spending time with friends.
What is the most painful mental pain?
Borderline personality disorder – Borderline personality disorder (BPD) has long been believed to be a disorder that produces the most intense emotional pain and distress in those who have this condition. Studies have shown that borderline patients experience chronic and significant emotional suffering and mental agony.
- Borderline patients may feel overwhelmed by negative emotions, experiencing intense grief instead of sadness, shame and humiliation instead of mild embarrassment, rage instead of annoyance, and panic instead of nervousness.
- People with BPD are especially sensitive to feelings of rejection, isolation and perceived failure.
Both clinicians and laymen alike have witnessed the desperate attempts to escape these subjective inner experiences of these patients. Borderline patients are severely impulsive and their attempts to alleviate the agony are often very destructive or self-destructive.
Suicidal ideation, suicide attempts, eating disorders ( anorexia nervosa, binge eating disorder, and bulimia nervosa ), self-harm (cutting, overdosing, starvation, etc.), compulsive spending, gambling, sex addiction, violent and aggressive behavior, sexual promiscuity and deviant sexual behaviors, are desperate attempts to escape this pain.
The intrapsychic pain experienced by those diagnosed with BPD has been studied and compared to normal healthy controls and to others with major depression, bipolar disorder, substance use disorder, schizophrenia, other personality disorders, and a range of other conditions.
Although the excruciatingly painful inner experience of the borderline patient is both unique and perplexing, it is often linked to severe childhood trauma of abuse and neglect. In clinical populations, the rate of suicide of patients with borderline personality disorder is estimated to be 10%, a rate far greater than that in the general population and still considerably greater than for patients with schizophrenia and bipolar disorder,
However, 60–70% of patients with borderline personality disorder make suicide attempts, so suicide attempts are far more frequent than completed suicides in patients with BPD. The intense dysphoric states which patients diagnosed with BPD endure on a regular basis distinguishes them from those with other personality disorders: major depressive disorder, bipolar disorder, and virtually all known DSM-IV Axis I and Axis II conditions.
- In a 1998 study entitled “The Pain of Being Borderline: Dysphoric States Specific to Borderline Personality Disorder”, 146 diagnosed borderline patients took a 50-item self-report measure test.
- The conclusions from this study suggest “that the subjective pain of borderline patients may be both more pervasive and more multifaceted than previously recognised and that the overall “amplitude” of this pain may be a particularly good marker for the borderline diagnosis”.
Feelings of emptiness are a central problem for patients with personality disturbances. In an attempt to avoid this feeling, these patients employ defences to preserve their fragmentary selves. Feelings of emptiness may be so painful that suicide is considered.
What is the most painful emotion?
The List: All the Feels: Every emotion ranked from worst to best 72. Worry
- It’s that rare combination of an emotion that’s both cripplingly powerful and utterly worthless.
- 71. Shame
- Particularly that of the religious variety.
- 70. Suffering
- Although some people sure seem to enjoy it.
- 69. Annoyance
- There’s a lot of great “negative” feelings, but this one ranks so low on the scale, like, what’s the point?
- 68. Embarrassment
- Because no one can make you feel as awkward as you.
- 67. Despair
- It’s the absence of hope, which you will see much higher on this list.
- 66. Envy
- You can’t always get what you want.
- 65. Anguish
- Some of the members of the Sad Family have benefits, but this one is pretty much just pain.
- 64. Contempt
- If you think you’re better than someone that probably means you aren’t.
- 63. Apathy
- That weird emotion that is really just the lack of better ones.
- 62. Hysteria
What happens when emotions fly off the rails. Also a great Def Leppard album.
- 61. Hostility
- What’s your problem, bro?
- 60. Frustration
- I have an ex-girlfriend who pronounced this “fustration,” which was, in and of itself, pretty frustrating.
- 59. Depression
- It really is the worst feeling, but it’s also motivated some great art over the years.
- 58. Disappointment
- That’s what you get for having hopes and dreams.
- 57. Jealousy
- Similar to envy, but ranked higher because of that sweet Gin Blossoms song.
- 56. Panic
- 55. Horror
It’s fun when it’s a movie theater. Less so when you’re being chased by a bear.
- 54. Rage
- “Anger is a gift.” – Rage Against the Machine
- 53. Regret
- It’s best if you can prevent this in advance, because it’s the worst.
- 52. Hatred
Haters gonna hate. And good for them.
- 51. Dread
- It’s like fear, only in advance of the thing you are actually afraid of, so yay for that.
- 50. Sorrow
- There sure are a lot of kinds of sad, huh?
- 49. Fear
- Usually a negative thing that keeps you from reaching your potential, but sometimes it also keeps you from being eaten by bears, so it’s not all bad.
- 48. Anxiety
- Nothing quite like constant irrational fears to keep you going through the day.
- 47. Boredom
- 46. Indifference
- 45. Disgust
It’s what kept you from enjoying Brussels sprouts, and you were wrong about that. Admit it.
- 44. Distrust
- It’s not fun, but sometimes it’s right.
- 43. Loneliness
It’s weird that a feeling can run so deep and be so wrong. You are never alone. Even when you’re pooping.42. Grief A deep sadness, but often an important one. If you need to feel grief, let yourself.
- 41. Outrage
- There’s so much of the faux variety going around, but a little genuine outrage can be a great motivator for change.
- 40. Guilt
It’s only worthwhile if it helps make you a better person. It’s a nice place to visit, but you wouldn’t want to stay.
- 39. Shock
- Not a great feeling, but it least it doesn’t last.
- 38. Loathing
- It’s hatred, but at least it’s passionate.
- 37. Surprise
- Bet you didn’t expect this to be in the middle of this list!
- 36. Pride
- It can be a good thing, but it’s also easy to have too much of it.
- 35. Desire
Can be good or bad, depending on what you do with it. Also a great Meg Myers song.
- 34. Interest
- It’s the right-swipe of emotions.
- 33. Zest
It’s a feeling. And also a soap.
- 32. Schadenfreude
- It’s really not cool to take pleasure in the misfortune of others, but this is such a cool word for it.
- 31. Pity
Take it from Mr.T.30. Hurt It’s going to happen. It just shows you’ve got feelings. No worries.
- 29. Curiosity
- Ranked lower if you’re a cat.
- 28. Wonder
- It’s wonderful, but we can do better.
- 27. Confidence
- It’s that feeling only a great deodorant can provide.
- 26. Shyness
- It’s nice, but it can stop you from doing all the things in life you’d like to.
- 25. Arousal
- 24. Affection
- Even better when it’s in private.
- 23. Satisfaction
- Pairs nicely with smugness.
- 22. Excitement
- 21. Lust
- Whether it’s for another person or just for life, it’s pure and primal, which is pretty cool.
- 20. Zeal
- It’s like the 5-Hour Energy of emotions.
- 19. Self-confidence
This is a good thing, as long as it’s real. Beware of people who project their own insecurities as a hyper-ized self-confidence.
- 18. Ecstasy
- Such a sweet feeling they made a drug for it.
- 17. Courage
- As long as it’s not around bears.
- 16. Relief
- That great feeling that comes along when the ones you were worried about did not.
- 15. Remorse
- Of all the guilty feelings, this is the one most likely to actually have a good outcome going forward.
- 14. Euphoria
- It’s an intense happy, not a sustainable one, but it’s fun while it lasts.
- 13. Pleasure
- It’s the low-grade happiness we take in so many things.
- 12. Awe
- This one goes away far too often in grown-ups, but you should be in awe almost every day if you think about it.
- 11. Angst
It’s the teenager of emotions. It’s not a good feeling, but it’s such great fuel.
- 10. Anger
- It’s important that you keep it in check and don’t let it take over your life, but it’s also why we have Slayer.
- 9. Hope
So many feelings are stuck in the past or focused on the present. This one is about the future.8. Contentment Our desire to constantly better ourselves is worthwhile, but it also devalues the ability to be in a moment and realize you have everything you need to be happy.
- 7. Trust
- This one is delicate and hard to rebuild when it’s broken, but it’s pretty great when it’s there, huh?
- 6. Gratitude
This is one that goes underrated. You can never have too much of this.
- 5. Joy
- This is the highest on the happy scale, most often experienced by children and those who remember what it’s like to be one.
- 4. Passion
- Whatever it’s applied to, it makes it better.
- 3. Sadness
An important lesson you should have learned from Mister Rogers: It’s OK to feel sad sometimes. If you don’t let yourself feel sad, it comes out as something even worse. Plus, sad songs are great.2. Happiness It’s simple enough, but it’s also our natural and intended state. Sometimes all you have to do is allow yourself to feel it.1. Love The Beatles were right. It really is all you need.
Can you mentally turn off pain?
Only Certain Kinds Of Pain Can Be Controlled With Your Mind – It’s first worth noting that not all kinds of pain can be tackled with our minds. Acute pain and chronic pain can, however, be addressed with your thoughts, Tolman says. “Now keep in mind if you walk into therapy with a broken arm, it’s not going to take that pain away,” she says.
- But chronic pain and pain without a source can be managed with your thoughts.
- There is a big emotional tie between pain and your thoughts, and by altering your thoughts you can alter the pain.” The CDC estimates that 20.4% of US adults live with chronic pain.
- And STAT reports that the most significant drivers in chronic pain are migraines, arthritis, and nerve damage — as well as emotional trauma.
Jeannie Sperry, a psychologist who specialises in pain rehabilitation at the Mayo Clinic, said that it’s rare for people to have chronic pain without also having anxiety or depression. “Often times, a person who experiences chronic pain will report that this pain becomes a part of their identity,” Tolman says.
Who has a higher pain tolerance?
Acute Pain Tolerance Is More Consistent Over Time in Women Than Men, According to New Research | NCCIH.
Will my pain ever go away?
Five things I wish I knew earlier in my journey with chronic pain I ‘ve been living with chronic pain for more than a decade. It began in 2009 with nerve damage after emergency groin surgery. Four years later, I fell and hit my head. That fall led to a constant headache, a whistling sound in my ear, back and hip pain, tingling and numbness in my hands and feet, electrical shocks in my legs, muscle soreness, and random pain and burning sensations throughout my body.
- Years later, after numerous doctor visits and tests, I was diagnosed with fibromyalgia, tinnitus, neuropathy, chronic fatigue, and depression.
- I had a hard time adjusting to the pain.
- I let my symptoms control me.
- My quality of life suffered along with my physical conditioning.
- Here are five things I wish I had known earlier in this journey, much of which I learned while attending a three-week outpatient program at the in 2012 and again in 2018.
Each of these would have made my journey easier and might help others living with chronic pain. Pain isn’t just physical. Chronic pain clearly affects the body, but it also affects emotions, relationships, and the mind. It can cause anxiety and depression which, in turn, can make pain worse.
At work, I couldn’t handle the stress. I had trouble concentrating, missed deadlines, and made mistakes. At home, I didn’t sleep well and was irritable. I was plagued by negative thoughts like, “Do I want to live like this the rest of my life?” When I reluctantly quit my job at the recommendation of my doctors, I lost more than a regular paycheck and valuable benefits like health insurance and retirement savings: I also lost a sense of self-purpose and self-worth.
As I came to understand the connection between pain and emotional issues, I included mental health care as part of my pain management program to help control my mood and manage stress. Pain isn’t always curable. Medical professionals don’t have all the answers, nor do they always have cures.
- There is no magic pill or intervention that makes chronic pain disappear.
- Sadly, some people with chronic pain may never be pain free again.
- To try to relieve my pain, I’ve bounced between all types of health care providers: primary care physicians, pain specialists, rheumatologists, neurologists, audiologists, physical therapists, surgeons, and psychiatrists.
I’ve been through X-rays, ultrasounds, MRIs, CT scans, and all sorts of other diagnostic tests. I’ve taken opioid painkillers, non-opioid painkillers, vitamins, and herbs; attended professional lectures; spent countless hours searching the internet; and even had surgery.
Some of these helped relieve my pain, some didn’t, and some even made things worse. Meanwhile, they all cost me time and money and delayed my pain rehabilitation. Not all pain means harm. We learn at an early age that touching something hot hurts. But the presence of pain doesn’t always mean danger. There are two types of pain: acute and chronic.
Acute pain is the body’s normal response to tissue damage or injury and needs immediate medical treatment. It heals and generally lasts less than three months. Chronic pain is an abnormal response and doesn’t improve with time. It can occur in the absence of tissue damage and persist long after the body heals.
- It changes how nerves and the brain process pain, as misfiring nerve signals continue to tell the body it hurts.
- By being able to tell the difference between new acute pain and chronic pain, I have changed how I react to chronic pain by not being so guarded or worried about it.
- Thoughts, feelings, and behaviors are connected.
Chronic pain makes it easy to feel distressed, to give up and become a victim. “Woe is me,” “life isn’t fair,” and other unhelpful thoughts increase one’s focus on pain and can make it worse. It fosters anger, frustration, and hopelessness. And it leads to what experts’ call pain catastrophizing — an exaggerated negative response toward actual or anticipated pain.
- I did my share of catastrophizing.
- When my symptoms first started, all I could think about was how much I hurt and if the suffering would ever end.
- I even journaled symptoms and rated my pain each day so I could share with my doctors what I was experiencing.
- I became overwhelmed. Move on.
- If chronic pain doesn’t mean more harm and there aren’t any magical medical answers, what’s left to do? Accept the pain as the “new normal,” adapt to it, and learn how to manage it.
Of course, that’s easier said than done. Here are I have found helpful to calm the body and mind and make it easier to function include:
Reduce pain behaviors. The body’s natural physical, vocal, and verbal reactions to pain, such as rubbing, wincing, groaning, limiting activity, and complaining, fuel anxiety and intensify pain. I try to avoid these behaviors so as not to draw attention to my pain. It’s harder to hurt when you don’t think about it. I often use watching a funny movie, listening to music, talking to a friend, or doing some other social activity to focus on something other than the pain. Exercise. While it may seem counterintuitive, movement helps reduce pain and improves conditioning. I try to walk each day even though my body hurts. Limit when needed. People with chronic pain often do too much when they are having good days and not enough when they are having bad days. I have learned limits and try to pace myself so I don’t worsen my symptoms. Lighten your load. Why make things harder than what they are? Techniques like good body mechanics make activities easier, not harder. Heavy lifting, for example, makes my pain worse. So instead of carrying a heavy load in one trip, I divide it into lighter loads and make multiple trips. Relax and ease tension. Pain and tension can form a viscous circle. Muscles tighten and put pressure on nerves resulting in even more pain. I do deep breathing and muscle relaxation exercises to help reduce tension.
Should I allow myself to feel the pain?
Should You Feel or Flee Your Emotions? – To a great extent, we live in a culture that resists and fears emotion. From the time we’re babies we’re taught to quickly shut off “negative” feelings like anger, sadness or pain. Yet, learning to suppress or overly control our emotions has serious consequences.
When we avoid our feelings, we tune out important clues as to who we are. We limit our capacity for self-understanding and fail to fully experience or shape our lives. The methods we adopt to numb ourselves to interpersonal pain from our earliest relationships tend to become engrained in us and solidified as early as 5 years old when we start to develop an awareness of loss and death.
These psychological defenses may have originally been created to protect us stressful circumstances, but they can go on to hurt us in our adult lives. My father, Dr. Robert Firestone, in his comprehensive theory of human behavior, Separation Theory, contends that the core conflict for all human beings is whether to live a life of feeling or to attempt to suppress our feelings in an effort to block out pain, from both interpersonal relationships and from existential issues.
- The problems that arise from attempting to deny our pain are many fold.
- For one, we cannot selectively cut out “negative emotions,” such as anger and sadness, while maintain the ability to feel joy and happiness.
- When we cut off our emotions, we become numb to life.
- We lack direction or meaning.
- We lose touch with our desires that could result in goal-directed behavior.
We often relive our past or live out prescriptions for our lives created in our childhoods. In order to make sense of our current actions and reactions, we must be willing to recognize and explore our emotions. Emotions can be healthy or unhealthy, adaptive or maladaptive, primary or secondary.
- Primary emotions are healthy, adaptive and function to help us survive and thrive.
- Secondary, non-adaptive, unhealthy emotions result from the judgments and internalized negative thoughts and beliefs we learn in the process of growing up.
- When we attempt to suppress or control our emotions rather than experience and work with them, they contribute significantly to our distress and maladaptive behaviors.
Last summer, I had the opportunity to take a workshop with Dr. Leslie Greenberg, the primary developer of Emotion-Focused Therapy, His approach focuses on the importance of emotions for creating psychological change. He believes that any attempt to help a person that does not put a strong emphasis on emotion is incomplete and inadequate.
- His method is designed to help people, accept, express, regulate, understand and transform emotion.
- Although certain emotions can feel threatening, as Dr.
- Greenberg’s work has shown, it’s possible to stay in touch with our feelings, while allowing them to serve a positive, adaptive purpose.
- Although many people are afraid of being overwhelmed by them, our emotions aren’t actually as menacing as we make them out to be.
They can be felt and released safely without overtaking us. As Dr. Greenberg said, “Emotion is not opposed to reason. Emotions guide and manage thought in fundamental ways and complement the deficiencies of thinking.” Allowing ourselves to fully experience our feelings can help us sort out what we really want and think, and how we can make our behavior consistent with those desires.
Feeling our emotions is very different from allowing them to rule our behavior. When we feel even our most unacceptable-seeming feelings in a safe and healthy forum, we’re actually less likely to act on them in destructive ways. It’s possible to feel hurt without acting victimized and to feel anger without lashing out.
It’s possible to feel fear without going into hiding and to feel heartbreak without breaking in two. Being able to feel our feelings actually makes us stronger and more resilient. However, none of us are born with the ability to regulate our emotions. We learn this from our earliest caretakers, so if they hadn’t mastered this ability themselves, it was difficult for them to model or teach us to regulate emotions in ourselves.
- If we didn’t learn adaptive and healthy ways of dealing with our feelings as kids, it can continue to limit us in many areas of our lives, especially those that hold particular meaning.
- That is why it’s so important to learn these skills at any stage in life.
- Emotion-Focused Therapy offers a way for people to work through their feelings by emphasizing awareness, acceptance, understanding and transformation.
This method can help individuals learn to tolerate and regulate their emotions. Through this approach, which Dr. Greenberg will discuss in his forthcoming webinar, “Importance of Emotion in Therapy,” people can learn to neither deny their emotions nor feed them until they feel overpowering.
As Dr. Greenberg put it, we can learn to live in “mindful harmony with our feelings, not attempt to control them.” We can all learn strategies to increase our tolerance for emotion. These include: 1. Sit with a feeling and breathe. One technique they teach people with chronic pain is to stop trying to avoid feeling discomfort.
This attempt at evading pain backfires, because the tension of warding off the sensation increases the pain. When an emotion arises, try not to resist or keep it down. Instead, try to relax and let yourself accept and feel whatever you feel. It’s okay to let yourself fully experience feelings of anger, sadness, pain or wanting.
Resist the temptation to judge these emotions or label them. If you can sit with these feelings, you can actually learn to be more comfortable with them.2. Don’t judge your emotions. No emotion is “bad.” Feelings are just feelings; they sometimes offer clues into your past and insight into what specific adaptations you made to cope early in your life.
For example, say you feel enraged whenever someone tells you to smile or to speak up. This emotion may not be a rational response in the present, but statements like these could be triggering something old in you such as the memory of a parent who wanted you to perform or put on a happy face.
- Remember our emotions don’t have to dictate our actions.
- We can be curious and open to what we feel, while actually becoming less likely to be controlled by these triggered emotions.3.
- Find ways to calm the feeling instead of feeding it.
- In other words, you shouldn’t avoid the feeling, but you also shouldn’t indulge in processes that would intensify it.
So, if you’re furious, or hurt, don’t spend time building a case or exaggerating the situation. Feel the emotion and stay with it until the wave builds and subsides. Then, let it go. Don’t over-identify with it or allow it to keep building and building by feeding it extra ammunition or trying to justify the feelings with thoughts.
- You can feel the full feeling without allowing it to skew or distort your rational point of view.
- Emotions shape every area of our lives, including who we are and how we function.
- When we’re willing to open ourselves up and experience our emotions fully, we gain insight and awareness into ourselves.
- Even maladaptive, negative feelings toward ourselves are important to express in order to experience the natural response of adaptive anger toward the source of the thought and the empathy and self-compassion that will follow.
Often, only after expressing these feelings are we able to make a meaningful shift in our self-perception that would be difficult to achieve otherwise. Remember, emotions will come and go, and all feelings are acceptable. We can learn to feel all of our feelings, while at the same time making rational decisions as to how we want to behave.
- In order to evolve or change, we have to feel our pain fully and make sense of it.
- This helps integrate our brain and allows us to build stronger relationships in the present.
- Though it may seem counterintuitive, if we delve in and feel our sadness, we’re more likely to feel love, gratitude and happiness as well.
Thus, acquiring the ability to process and regulate our emotions in healthy ways is one of the most important skills to live our best life. Join Dr. Les Greenberg for the Webinar ” Importance of Emotion in Therapy,”
Why do I find comfort in pain?
The Comfort of Familiar Pain – When something is familiar, it usually feels safe, steady, and unchanging. When we have been repeatedly hurt, or held on to hurts long enough, these feelings and thoughts become familiar. As a result, we are well acquainted with them and become accustomed to how they feel.
Can CIPA be cured?
CIPA (Congenital Insensitivity to Pain with Anhidrosis) For some, the idea of having the inability to feel pain may seem ideal. Although pain may not be one of our preferred sensations; it is very important. Without the feeling of pain, you are more at risk of sustaining serious injuries.
It signals that something is wrong with your body that requires immediate attention. There are individuals who are insensitive to pain. This can be the result of inherited disorder known as CIPA (congenital insensitivity to pain with anhidrosis). This is an extremely rare disorder which may also cause a person to produce very little sweat or none at all and makes them incapable of feeling temperature.
These symptoms appear early in childhood, typically at birth or during infancy. Unintentional injuries are very common in children with CIPA. They may bite their tongues, fingers or lips, causing severe damages and in some cases amputation. Other complications associated with the disorder is high fever as the body is unable to sweat and lower temperatures, chronic bone infections as a result of chronic trauma or delay in healing of skin and bone injuries.
In some cases, individuals may have intellectual disabilities. The cause of CIPA is attributed to mutations in the NTRK1 gene. Mutations in this gene lead to a loss of the sensory neurons, as well as the ability to feel pain. Diagnosis of CIPA is usually confirmed after a complete evaluation of infants with recurrent fevers, who frequently bite their tongue, fingers or lips.
In older individuals, an evaluation is required if they continue to have traumatic injuries. Assessments of the sensory and autonomic functions are used to form a complete, clinical diagnosis. There is no cure for CIPA but the condition is manageable with the help of a team of medical professionals that typically include specialists in orthopedics, pediatrics, dermatology, ophthalmology and dentistry.
Parents of children with the disorder are strongly advised to keep a watchful eye at all times for signs of injury and to remove items that may result in accidents. For more information about CIPA and other rare medical conditions, please visit the National Organization for Rare Disorders website, All content of this newsletter is intended for general information purposes only and is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment.
Please consult a medical professional before adopting any of the suggestions on this page. You must never disregard professional medical advice or delay seeking medical treatment based upon any content of this newsletter. PROMPTLY CONSULT YOUR PHYSICIAN OR CALL 911 IF YOU BELIEVE YOU HAVE A MEDICAL EMERGENCY.
Why do people with CIPA not live long?
The Absence of Pain Author: Jessica LearInstitution: West Virginia University Date: July 2011 As soon as he stuck the needle into the newborn baby’s heel, Dr. Yashuhiro Indo knew something was wrong. “I was thinking out loud, why does this baby not cry?'” said Dr.
- Indo, a pediatrician and molecular geneticist from Kumamoto University.
- There exists a small group of people who, like this baby, have never felt the unpleasantness of a shot, the sharp pain of a paper cut, or a sudden burn from a hot surface.
- These people are insensitive to pain and are said to have hereditary sensory and autonomic neuropathy (HSAN).
One version of this disorder, called congenital insensitivity to pain with anhidrosis (CIPA), is an extremely rare disorder of the nervous system in which the body is insensitive to pain and temperature. The repercussions of this disease are devastating.
- Consequences of a pain-free lifestyle To those of us who feel pain every day, the notion of a painless existence is perhaps initially appealing.
- Scrapes, bruises, and burns would still be present on our bodies, but would not feel any differently from the rest of our body.
- While a pain-free life might seem like a pleasant way to live, it is actually extremely dangerous.
Because it is congenital, children with CIPA cannot be taught that harming the body is a bad thing since they never feel the consequences. Normal children learn to associate negative consequences with “bad” actions through experience, most often involving pain.
- The child then knows that taking that action again would cause them further pain, and so they do not repeat it.
- For instance, if a child jumps off of a tree, a painful landing will reinforce a hesitancy to do so in the future.
- Children with CIPA can never learn these lessons.
- These children will jump out of the tree, experience no pain, and are more likely to repeat that action.
They can even sustain multiple-fracture bone injuries. Children with CIPA often gnaw on their fingers to the point where it can endanger their life because they don’t understand that damaging the fingers is harmful. The lips and tongue are other common targets for children with CIPA.
Most people afflicted with the disorder do not live past age 3, though not all deaths are due to the lack of pain. In fact, half of CIPA deaths are due to overheating because of the person’s inability to produce sweat. This causes hyperthermia, or extremely elevated body temperature, which then leads to death.
Excessive self-mutilation can also lead to death in some cases. There have been an extremely small number of CIPA patients who have lived past age 25. Developing CIPA CIPA is caused by a genetic mutation in the gene that codes for the neurotrophic tyrosine kinase receptor.
Though this mutation is known to cause CIPA, the exact mechanism is not yet completely understood. Dr. Wen-Chin Weng, a pediatric neurologist at National Taiwan University, explained that “animal studies are needed in the future to understand the mechanism about how mutations lead to CIPA.” This receptor spans the membrane of pain-detecting cells and is expressed during development.
Pain-detecting cells can only survive development if a particular protein binds to the receptor. However, in CIPA patients, the protein that normally binds to the receptor on the pain cells cannot bind because the receptor is not produced. Since the protein is not bound, it is not able to affect the cell, and the pain-detecting cells eventually die.
- People with CIPA are therefore born without the ability to sense pain.
- CIPA is an extremely rare disorder.
- Only 17 people live with the disease in the United States. Dr.
- Weng also noted the rarity of CIPA in her country: “We have only one case report.
- This is the youngest and second reported patient in our country, as this a very rare disease in Taiwan.” Therapies and research Despite the odds, scientists have developed a few treatments for CIPA.
The most commonly used treatment is a drug called Naloxone, which is currently used to treat opioid overdoses. It aims to counteract severe, life-threatening depression of the nervous system. Opioids block the sensation of pain and Naloxone stops this blockage.
- This treatment only works in some CIPA patients and its mechanisms are not entirely known.
- One of the harsher, but effective treatments of CIPA is to remove all of the patient’s baby teeth when they first come in.
- Sometimes children with CIPA can completely chew their tongues off for lack of feeling.
- This can cause the child to bleed to death if the behavior or disease is not diagnosed.
This removal saves the fingers, lips, and tongue of children who are unable to stop before damage is done. By the time the patient’s adult teeth begin to grow in, he or she will likely have developed an understanding of healthy behavior. Most of the studies on CIPA have focused more on its mechanism in development more than on creating possible treatments for the disorder.
- Dr. Felicia Axelrod, a pediatric neurologist at New York University who studies CIPA, highlighted the importance of this research.
- Understanding mechanisms of autonomic control and pain perception in CIPA and FD is very special, as these are genetic models that help us understand function and maintenance of the autonomic and sensory nervous systems,” she said.
Scientists have begun to identify pathways absent in CIPA patients that may be essential for developing the entire nervous system, not just pain neurons. “Right now we are still trying to understand the mechanisms, but the goal of course will be how to use this knowledge to help the patients,” Dr.
- Axelrod said.
- Why we need pain Pain is as essential to our lives as breathing and walking.
- It is part of who we are and is among the most essential things we need to survive.
- CIPA serves as important model for how pain works in our bodies.
- As noted by Dr.
- Indo, “CIPA can serve as a useful model to determine mechanisms of development and maintenance of neurons in autonomic, sensory and central nervous systems.” By using this model, scientists can more fully understand the mechanisms of the nervous system while taking one step closer to treating patients with CIPA.
Further Reading Axelrod, F.B., Gold-von Simson, G. (2007) Hereditary sensory and autonomic neuropathies: types II, III, and IV. Orphanet Journal of Rare Diseases, 2, 39-43. Beigelman, A., Levy, J., Hadad, N., et al. (2009) Abnormal neutrophil chemotactic activity in children with congenital insensitivity to pain with anhidrosis (CIPA): The role of nerve growth factor.
Clinical Immunology, 130, 365-372. Indo, Y. (2009) Nerve growth factor, interoception, and sympathetic neuron: Lesson from congenital insensitivity to pain with anhidrosis. Autonomic Neuroscience, 147, 3-8. Lambert, K. (2007) How CIPA Works. HowStuffWorks.com. Lin, Y., Su, Y., Weng, W., et al. (2010) Novel Neurotrophic Tyrosine Kinase Receptor Type 1 Gene Mutation Associated With Congenital Insensitivity to Pain With Anhidrosis.
Journal of Child Neurology. : The Absence of Pain
Why can’t I cry anymore?
Why can’t I cry anymore? Mental health causes – Besides physical ailments, there are plenty of mental and emotional reasons why someone may struggle to cry. These include: Depression It might sound contradictory but many people with depression struggle to cry.
- That’s because depression can manifest itself in different ways.
- When you think of depression, you might picture someone experiencing knock-you-off-your-feet sadness and distress.
- But this isn’t the case for everyone.
- In fact, some people say their depression feels more like overwhelming numbness or emptiness,
They may feel so unemotional or “flat” that even positive events don’t elicit a response. Ultimately, this can result in an ability to cry. Anhedonia Imagine you lived and breathed crafting but, one day, it no longer brought you joy. Or, what if, the idea of reuniting with an old friend made you feel nothing. It’s not an uncommon experience and it’s called anhedonia, Simply put, anhedonia is when you lose interest in the social activities and physical sensations that you once enjoyed. It’s a symptom of many mental health conditions, including depression, schizophrenia and bipolar disorder,
Not all people with these mental health conditions experience anhedonia. But those who do may struggle to cry. Repressed emotions Do you bottle up your emotions? Maybe you feel like you’ve got to put on a brave face and ‘just get on with it’? If so, it may explain your inability to turn on the waterworks.
Emotional crying involves getting in touch with your feelings. So people who repress or disconnect from their emotions may struggle to cry Societal pressure Some people find it difficult to cry because of societal pressure or their internalised beliefs about crying. You may have subconsciously adopted these notions about crying in childhood. Let’s say your parents struggled to express their emotions and rarely cried. As you grew up, you may have followed their example and held back your tears, even when you had a good reason to bawl.
Your parents might have even told you off for crying, which might lead you to believe that your tears are ‘wrong’ or a sign of misbehaviour. You may also have been swayed by cultural or societal beliefs. For instance, studies suggest that women typically cry more than men, and the difference may be more pronounced in countries whereby the culture allows for greater emotional expression.
We’re all aware of the phrases “man up” or “men don’t cry”. Whilst they might seem harmful on the surface they can do a lot of damage. That’s because they suggest that expressing yourself is a sign of weakness. And that couldn’t be further from the truth.