Bemaj Pharmacy

Over-the-counter pain relievers, such as ibuprofen (Advil, Motrin IB, others) or naproxen sodium (Aleve), at regular doses starting the day before you expect your period to begin can help control the pain of cramps. Prescription nonsteroidal anti-inflammatory drugs also are available.

Is it OK to take tablet for period pain?

Dr Suman Lal, Associate Director- Obstetrics and Gynaecology, Max Hospital said, “one mild painkiller with a gap of 12 hours can be taken during period pain.” (Photo: Getty Images/Thinkstock) For many women, the menstruation cycle is accompanied with painful cramps which not only affect day-to-day activities but can be really difficult to bear.

In such a situation, women may consider taking a painkiller to ease the pain, but is it safe to take the pills? Buy Now | Our best subscription plan now has a special price There is so much confusion around taking painkillers during the periods, but Dr Tanaya, a doctor, said that it is okay to take pills during menses.

“It is totally okay to take painkillers if you get pain because of period cramps. Taking these painkillers will not make you infertile or harm your uterus. Periods are a difficult time and it’s important to keep yourself comfortable,” she wrote in her Instagram post.

Agreeing with her, Dr Suman Lal, Associate Director- Obstetrics and Gynaecology, Max Hospital said, “one mild painkiller with a gap of 12 hours can be taken during period pain.” Explaining the reason behind the period pain, Dr Tanaya wrote that it occurs because your body secretes substances called ‘prostaglandins’ that help squeeze your uterus to get the period blood out.

According to her, most period painkillers (like Meftal Spas) work by relaxing the uterus, so it does not squeeze itself that hard which eases pain. However, regular painkillers (like aspirin, diclofenac, ibuprofen) work by indirectly reducing prostaglandin activity, so the squeezing action is reduced and you are not in pain.

Dr Tanaya warned against overdose on the pills. “Do not consume more than one every eight hours. Excessive consumption of painkillers can harm your kidneys and your stomach, but one or two painkillers every other month are not enough to cause that damage in an average person,” she explained. “And if your pain is not eased even after taking painkillers, or you are in extreme pain, please see a doctor.

There could be an underlying condition that needs investigation,” she added. During the menstruation cycle, we might feel lazy. Dr Suman suggested a few ways which can help relieve pain. “In addition to using heat and consuming peppermint tea, you can also lessen cramping by avoiding particular foods such as fried meals, milk and other dairy products, fatty foods, and caffeine.

1. Applying heat to your back or abdomen can help ease your pain since heat can relax the muscles responsible for cramping,
2. Period discomfort can be significantly reduced by using a heating pad or taking a warm bath,” Dr Suman elaborated.
3. Also, she suggested doing exercise as it encourages the body’s natural production of endorphins, which work to reduce pain perception.

📣 For more lifestyle news, follow us on Instagram | Twitter | Facebook and don’t miss out on the latest updates!

Which painkiller is best during periods?

Over-the-counter pain relievers, such as ibuprofen (Advil, Motrin IB, others) or naproxen sodium (Aleve), at regular doses starting the day before you expect your period to begin can help control the pain of cramps. Prescription nonsteroidal anti-inflammatory drugs also are available.

What is the strongest pain killer for period pain?

Other self-help measures to try – You could also try:

stopping smoking – smoking is thought to increase the risk of period painexercise – you may not feel like exercising during a painful period, but being active may reduce pain; try some gentle swimming, walking or cyclingheat – putting a heat pad or hot water bottle (wrapped in a tea towel) on your tummy may help reduce painwarm bath or shower – taking a warm bath or shower can relieve pain and help you relaxmassage – light, circular massage around your lower abdomen may also help reduce painrelaxation techniques – relaxing activities, such as yoga or pilates, may help distract you from feelings of pain and discomfort transcutaneous electronic nerve stimulation (TENS) – a small battery-operated device that delivers a mild electrical current to your tummy to help reduce pain

Why is my period so painful?

This pain is caused by natural chemicals called prostaglandins that are made in the lining of the uterus. Prostaglandins cause the muscles and blood vessels of the uterus to contract. On the first day of a period, the level of prostaglandins is high.

Why is my period pain so bad?

Doctors think that the main cause is an increase in the amount of prostaglandins in your womb (uterus) around the time of your period. Prostaglandins are chemicals that cause the muscles of your womb to tighten. This tightening of the muscles can temporarily reduce the blood supply to your womb, which causes pain.

What makes period cramps worse?

From Mayo Clinic to your inbox – Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Click here for an email preview. To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you.

If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices.

You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. During your menstrual period, your uterus contracts to help expel its lining. Hormonelike substances (prostaglandins) involved in pain and inflammation trigger the uterine muscle contractions.

Endometriosis. Tissue that acts similar to the lining of the uterus grows outside of the uterus, most commonly on fallopian tubes, ovaries or the tissue lining your pelvis. Uterine fibroids. These noncancerous growths in the wall of the uterus can cause pain. Adenomyosis. The tissue that lines your uterus begins to grow into the muscular walls of the uterus. Pelvic inflammatory disease. This infection of the female reproductive organs is usually caused by sexually transmitted bacteria. Cervical stenosis. In some women, the opening of the cervix is small enough to impede menstrual flow, causing a painful increase of pressure within the uterus.

You might be at risk of menstrual cramps if:

You’re younger than age 30 You started puberty early, at age 11 or younger You bleed heavily during periods (menorrhagia) You have irregular menstrual bleeding (metrorrhagia) You have a family history of menstrual cramps (dysmenorrhea) You smoke

Menstrual cramps don’t cause other medical complications, but they can interfere with school, work and social activities. Certain conditions associated with menstrual cramps can have complications, though. For example, endometriosis can cause fertility problems.

Why don’t painkillers help my cramps?

Q: Even with pain relievers, I get bad cramps with my period. What else can I do? Q: Even with pain relievers, I get bad cramps with my period. What else can I do? Blame menstrual cramps on the production by the uterus of hormonelike chemicals known as prostaglandins.

Some women make more prostaglandins or are more sensitive to them than others, so they may have stronger and more frequent cramps (actually, uterine muscle contractions) during the first day or two of menstruation, or they may find that the usual painkillers don’t bring relief. If OTC drugs don’t work for you, your doctor may prescribe stronger versions of NSAIDs like ibuprofen (Advil) or naproxen (Aleve).

All meds work best if you take them at the first sign of symptoms and for the first day or two of your period. Birth control pills also help reduce menstrual cramps and heavy bleeding.

Is it okay to take ibuprofen every period?

Long-Term Effects of Ibuprofen – Taking an over-the-counter pain reliever, especially after consulting with your physician, from time to time like ibuprofen for menstrual cramps is usually considered safe. However, even taking 400mg to 600 mg every now and then can have a few short-term effects such as:

HeartburnNauseaGasConstipationStomach pain

Although these short-term side effects are not considered life-threatening or serious, it’s good to know that these can happen after taking ibuprofen for heavy periods, Also, you should be careful about taking ibuprofen for period cramps if you plan to drink alcohol later that day.

Stomach bleeding or ulcersKidney damageIncreased blood pressureLiver failureAllergic reactionsHeart attack or stroke

Some of these serious health conditions are contingent on having a personal or family history of heart, clotting, or liver issues before taking ibuprofen. We’ll dive deeper into two serious long-term effects of ibuprofen so you can be aware of the potential risks.

Do menstrual cramps worsen with age?

Secondary dysmenorrhea – Secondary dysmenorrhea is the less common type of cramps and is caused by a medical condition like an infection, premenstrual dysphoric disorder (PMDD), endometriosis, uterine fibroids or ovarian cysts. These menstrual cramps often worsen with age and can last for the entire duration of your period.

Does period pain get worse with age?

Is your period pain getting worse with age? A gynaecologist explains why Menstrual cramps are a nightmare, but you can’t do much to avoid them. Many women will notice an ease in their pain as they age. However, that is not the case for others who experience even worse cramps with age.

Is your period pain or dysmenorrhea turning problematic with age? Unfortunately, it is possible for women to experience worse period pain as they grow older, especially in their 30s and 40s. The unbearable pain can come along with other symptoms such as irregular periods, pain during sex, foul-smelling vaginal discharge.

Some conditions also require medical attention. If you are experiencing unbearable period pain or any of these symptoms, your next step should be to visit your doctor where you can discuss your condition and get appropriate treatment for it if necessary. Those excruciating menstrual cramps can have multiple reasons. Image courtesy: Shutterstock

Is period pain similar to Labour pain?

During menstruation, chemicals called ‘prostaglandins’ form in the lining of the uterus. They cause muscle contractions in the uterus, which can trigger pain and decrease blood flow and oxygen to the uterus. Similar to labor pains, these contractions can cause significant pain and discomfort.

Why do periods hurt so much on the first day?

For many women, it’s the first sign that their period is coming—or has arrived. The unmistakable feeling of menstrual cramps. Ugh. Grab the blankets and hot tea. Here we go again. More than half of women who menstruate have some pain for a day or two each month.1 Although the pain is usually mild, some women experience severe pain that keeps them from doing their normal daily activities for several days a month.1 That severe pain can bring along some unwelcome friends, including diarrhea, nausea, vomiting, headache, and dizziness.1 So, period pain can bewell, a major pain.

Many of us have just come to accept it. But should we? And why are we in pain anyway? Let’s dig a little deeper. There are two types of period pain The technical term for period pain is dysmenorrhea (dis-men-uh-REE-uh). And there are two types: primary and secondary. Primary dysmenorrhea is the name for common menstrual cramps that rear their ugly heads every month.

This pain comes before or during your period and is caused by natural chemicals called prostaglandins that are made in the lining of the uterus.1 Prostaglandins cause the muscles and blood vessels of the uterus to contract, which is what helps the uterine lining to leave the body.

• On the first day of a period, the level of prostaglandins is high.
• But as the lining of the uterus is shed during your period, the level goes down.
• This is why your pain tends to decrease as your period progresses.1 Pain may range from mild to severe and you may feel it most in your lower abdomen, back, or thighs.2 You might also have other symptoms, like nausea, vomiting, fatigue, and diarrhea.2 For most women, this type of period pain gets less painful as we get older.3 Secondary dysmenorrhea is pain caused by a disorder in the reproductive organs.1 Pain from secondary dysmenorrhea usually begins earlier in the menstrual cycle and lasts longer than common menstrual cramps.2 For example, the pain may begin a few days before your period starts, get worse as your period continues, and not go away after it ends.

You usually don’t have nausea, vomiting, fatigue, or diarrhea.2 Some of the conditions that can cause secondary dysmenorrhea include:

• Fibroids —Fibroids are growths that form on the outside, on the inside, or in the walls of the uterus. Small fibroids usually don’t cause pain, but fibroids located in the wall of the uterus can be very painful.1-3
• Endometriosis—Tissue that lines the uterus (the endometrium) grows in areas outside of the uterus. This tissue breaks down and bleeds during your period and can cause pain.1-3
• Adenomyosis—Tissue that normally lines the uterus grows into the muscle of the uterus, which can cause the uterus to increase in size and cause abnormal bleeding and pain.1,2
• Ovarian cysts—Cysts are fluid-filled sacs on the ovary. Most ovarian cysts don’t cause any symptoms, but some can cause pain during your period or at ovulation.3

Secondary dysmenorrhea pain can also result from defects in the uterus, fallopian tubes, and other reproductive organs and from certain medical conditions that can flare up during a period, like Crohn’s disease and urinary disorders.1 How to relieve the pain A good idea is to start simple.

1. Although your urge may be to curl up into a ball in a dark room, getting out and moving around is a better plan.
2. Even a walk may help improve how you feel.
3. Next, over-the-counter medications called nonsteroidal anti-inflammatory drugs (NSAIDs) such as naproxen, ibuprofen, or aspirin can help relieve menstrual pain.

It’s also a good idea to track your periods, including symptoms and pain, in a diary or app. That way, if your pain worsens or your symptoms change, you have a history you can share with your doctor or nurse. When to talk to a doctor First, don’t ever think your pain isn’t worth mentioning to your doctor.

• Sure, menstrual pain is common, but your doctor can help determine if the pain you’re experiencing is typical or if it could be indicative of other issues.
• Talk to your doctor or nurse if over-the-counter pain medicines aren’t helping or if the pain is getting in the way of your daily life.
• Your doctor will ask you questions and do some tests, including possibly a physical exam, to help determine if your pain could be caused by primary or secondary dysmenorrhea and if treatment is necessary.

Take a look at our Doctor Discussion Guide to help you prepare for your next visit. Treatment for the pain Treatment depends on what is causing your pain. Your doctor may recommend hormonal medications in the form of a pill, intrauterine device, or injection to help with the pain.

• Another option could be medical procedures such as intrauterine tissue removal procedures and laparoscopic radiofrequency ablation, both of which require little to no incisions and are treatment options for women experiencing the disruptive symptoms of fibroids.
• The bottom line is although period pain is common, it can also be a sign of underlying issues.

Your doctor can help you determine the best way to move forward. Take a quiz to learn more about what your period pain might be trying to tell you. References:

1. American College of Obstetricians and Gynecologists. Dysmenorrhea: painful periods. https://www.acog.org/womens-health/faqs/dysmenorrhea-painful-periods, Accessed April 15, 2022.
2. Cleveland Clinic. Dysmenorrhea. https://my.clevelandclinic.org/health/diseases/4148-dysmenorrhea, Accessed April 15, 2022.
3. US Department of Health and Human Services. Office on Women’s Health. Period problem: menstrual pain (dysmenorrhea). https://www.womenshealth.gov/menstrual-cycle/period-problems, Accessed April 15, 2022.

How much period pain is normal?

How much period pain and flow is normal? – Mild to moderate cramps for one or two days during your menstrual cycle is usually normal. But many women experience painful and intense menstrual cramps that can feel debilitating and interfere with everyday activities and exercise.

Can I call in sick for period pain?

Period leave — also known as menstrual leave — has existed for decades in some parts of the world. But in the United States, people rarely experience it in workplaces. So, what’s it all about? Is period leave all it’s shaped up to be, or are there some hidden disadvantages to consider? And how can you introduce it in your workplace? Read on to find out answers to all of the above and more.

Period leave is a workplace policy that gives people time off while on their period. A workplace provides this leave in addition to standard sick leave. Generally, the expectation is that people will only use period leave if they’re unable to work — for example, if they’re in significant pain or discomfort.

But there isn’t a set definition or set number of days a person can take off. Such leave may be paid in some places and unpaid in others. Some employers may allow people flexible options, such as the ability to work from home instead of taking a day off.

Period leave started decades ago in countries like Russia and China, with the aim of “protecting” fertility levels. Now, there’s a growing movement to introduce it universally and normalize the effects periods can have on a person. While you’ll find period leave policies in places like Japan, Indonesia, and Mexico, it’s still a rare sight in the U.S.

In countries where there’s no national policy, like the U.K. and Australia, some employers have introduced their own. Some offer one paid day of period leave a month that needs a sign-off by a manager beforehand. Others give employees a choice : Take a day of leave, work from home, or temporarily move to a more comfortable part of the office.

A few employers in the U.S. have followed a similar path. Software company Nuvento allows staff to take one paid day of period leave per month, and astrology company Chani offers “unlimited menstrual leave for people with uteruses.” But right now, there’s no federal law that requires an employer to provide paid sick leave, let alone paid period leave.

Demand is potentially building, though. A 2019 survey involving 600 people found that 45% would support menstrual leave in the U.S. When you join a new company, the organization typically provides you with the company policies, such as sick leave. People will usually include period leave in this category.

• If you’ve been in a job for a while but aren’t sure if your employer offers period leave, ask a manager or the human resources department for a copy of the sick leave policy.
• You can specifically ask about period leave if you feel comfortable doing so.
• It’s possible to take time off for period-related symptoms under standard sick leave, though this can be tricky if your employer requires you to tell them why you need time off.

Depending on the company, this leave may be paid or unpaid. If your workplace’s sick leave allowance is generous, you may have enough days each year to take time off when on your period and when you’re feeling unwell for other reasons. But some sick leave policies may be insufficient — by taking days off for your period, you may run the risk of having no sick days available for other situations.

To prevent issues like the above, it might be worthwhile to speak with your employer about introducing period leave. Templates exist to help companies implement such a policy. Plus, you can point your employer to resources, like the above survey, to show the growing demand for period leave and the increase in annual productivity they are likely to see.

It’s also a good opportunity to promote more flexible working for all — even people who don’t have periods may welcome the idea of being able to work from home more often or take days off for issues that don’t fall under “standard” sick leave policies or that they feel uncomfortable discussing.

Indeed, not everyone who has a period may wish to take time off during it. Some may want to work from home when possible, while others may wish to work in a more comfortable part of the office, rather than at their desks. It’s also important to discuss staff education, inclusivity, and privacy if an employer implements a period leave.

For example, not everyone who menstruates will feel comfortable telling their employer when they have their period. One way to navigate this issue is to log period leave as standard sick leave and ensure the sick leave policy specifically mentions menstrual symptoms and covers enough days for this throughout the year.

Introducing period leave into the workplace can have myriad benefits, though there is a lack of research on the topic. By having open conversations about periods and their effects, people who menstruate may feel more comfortable discussing their health with employers and other staff members. This can eliminate the stigma around menstruation, boost well-being, and increase workplace productivity and company loyalty.

And those who still don’t feel comfortable openly discussing their menstruation — for example, nonbinary or transgender people — have the option not to disclose it if the policy categorizes period leave as part of standard sick leave. Plus, some companies who have implemented menstrual leave find that even those who don’t menstruate support the idea, as it promotes looking after one’s body and adjusting one’s working day to suit.

1. If companies implement period leave inclusively, employees should not typically have to disclose their menstrual status, instead labeling it as sick leave.
2. Requiring staff to tell their employer they wish to take period leave specifically runs the risk of them being forced to “out” themselves, potentially leading to further discrimination.

There’s also a concern that period leave policies could support the myth that people are incompetent and irrational when on their periods, which may have a detrimental impact on their career progression, salary levels, and workplace relationships. Indeed, in the 1980s in Japan, people who took period leave faced discrimination and harassment from employers.

• Additionally, a 2019 study reported that almost half of participants believed a period leave policy in the U.S.
• Would only have negative effects such as discrimination, with some respondents from the same study stating that menstruation isn’t debilitating for everyone.
• Therefore, it’s vital that managers actively promote such policies and even take period leave themselves, when appropriate, to normalize it.

Of course, there’s also the issue that people who don’t menstruate may feel discriminated against, as they’re not entitled to extra leave. Offering more annual sick leave and announcing that it includes period-related symptoms is one way to avoid discrimination complaints.

And ensuring that staff doesn’t have to state why they’re taking sick leave can protect employees who may not feel comfortable discussing menstruation needs. Ultimately, people need to feel able to take time off during their period or work in a more flexible way for any form of menstrual leave to work.

Therefore, inclusivity and confidentiality must be a priority. But exactly what that looks like is likely going to be a work in progress for some time. Still, if you’d like to see period leave in your workplace, there’s a chance to have a conversation with your employer about the advantages and highlight other companies who are paving the way.

• Lauren Sharkey is a U.K.-based journalist and author specializing in women’s issues.
• When she isn’t trying to discover a way to banish migraines, she can be found uncovering the answers to your lurking health questions.
• She has also written a book profiling young female activists across the globe and is currently building a community of such resisters.

Catch her on Twitter,

Can I kiss my wife during her periods?

Story highlights – Kissing is not only fun, it can be healthy A smooch helps reduce your blood pressure It can also reduce cramps and headaches upwave.com — Ah, the kiss. It can be so many things: sweet, loving, awkward, intense, transporting, disappointing, boring, sublime, life altering.

• On the delicious and passionate side of the spectrum, a smooch can be a heart-healthy micro workout, a hormone releaser and a mood booster.
• It’s also fun – and a great way to connect with the person you care about.
• Sex, as wonderful as it is, can be perfunctory,” says Andréa Demirjian, author of ” Kissing: Everything You Ever Wanted to Know about One of Life’s Sweetest Pleasures,” “Kissing is intimate: You’re right there in the space of your soul.

It gets to the core of your heart and spirit because it’s such a lovely way to express and receive love and affection. A kiss a day really can keep the doctor away.” Making out isn’t just good for your emotional heart, it gives your anatomical one a workout, too.

1. Issing passionately gets your heartbeat revved in a healthy way that helps lower your blood pressure,” says Demirjian.
2. It dilates your blood vessels – blood is flowing in a good, solid fashion and getting to all your vital organs.” “Kissing is great if you have a headache or menstrual cramps,” says Demirjian.

You may be inclined to wave away advances when you’re curled into an achy ball, but the blood-vessel dilation brought on by a good long smooching session can really help ease your pain. In fact, Demirjian recommends replacing the ol’ “Not tonight, dear – I have a headache” line with, “Honey, I have a headache.

• Come kiss me!” A smooch-a-thon gets all, er, fluids flowing – including your saliva.
• When you’re kissing, you’re secreting more saliva in your mouth,” says Demirjian.
• That’s the mechanism that washes away the plaque on your teeth that leads to cavities.” (So much more fun than gargling!) “If you’re feeling stressed or rundown, a little kissing or lovemaking actually the elixir you need to feel better,” says Demirjian.

“It will relax, restore and revitalize you. The feel-good chemicals in the brain get percolating: serotonin, dopamine, oxytocin – things you can get from the rush of exercising.” It can’t compare to 30 minutes on the elliptical, but a vigorous makeout session can burn 8 to 16 calories per smooch, says Demirjian.

• Issing and lovemaking can be a vigorous exercise if you’re fully engaged,” she says.
• You need to have a passionate kiss, but it doesn’t have to be a 10-hour makeout session.” One German study found that men who got a nice juicy kiss from their wives before leaving for work made more money.
• If he leaves his home happy, he’s more productive at work because he’s not feeling emotionally distressed, so he’s going to make more money,” explains Demirjian.

“Kissing has so much to do with your self-esteem and feeling loved and connected.” Per Demirjian, deep kissing can shape up the neck and jawline, which are often trouble spots for those concerned about looking older. “Your mouth has a number of facial muscles,” she says.

• When those are engaged in kissing, you can tighten and tone them.” It can be an excellent way to check out a potential partner for sexual compatibility before getting naked and emotionally involved, says Demirjian.
• But if your very first liplock with a new partner is meh, she recommends giving him or her one more shot.

“Sometimes during the first kiss, people are feeling awkward, nervous or embarrassed,” she says. “That might not breed the most seductive, sexy experience.” Second kiss is crappy, too? That’s your cue to take your lips – and the rest of you – elsewhere.

Can we take I pill during periods?

It is safe or not. I did sex during periods. I take I pill in 24 hours for stop pregnan. Health Query Yes you can have sex even during menstruation, it will be little messy but it can be managed easily. No need to take ipill or any form of contraception if you have sex during menses as you can not get pregnant, during that time. As you already took ipill, menses can come little irregular for some time. 1 person found this helpful ✕ Health Check 360 Suggestions offered by doctors on Lybrate are of advisory nature i.e., for educational and informational purposes only. Content posted on, created for, or compiled by Lybrate is not intended or designed to replace your doctor’s independent judgment about any symptom, condition, or the appropriateness or risks of a procedure or treatment for a given person.

Do painkillers affect period flow?

It’s normal for your period to change slightly from month to month – your flow might start a little earlier or later or be a little heavier or lighter. But if your menstrual cycle is all over the place every month, a few things could be to blame. Pregnancy is the most obvious reason for a missed period, but certain medical conditions, changes in your work or exercise habits, or even stress also can mess with menstruation.

And in some cases, so can your prescriptions, Birth control pills or hormonal IUDs typically make your periods lighter, shorter, and more regular. They’re sometimes prescribed as a treatment for women who have endometriosis, a condition that can cause heavy menstrual bleeding and very painful cramps.

However, if you take the progestin-only “mini-pill,” your cycle may be less regular at first. Some women have bleeding in between their regular periods for a few months after starting the medication. And some women notice missed periods in the months after they stop birth control pills, so if you’re trying to get pregnant, talk to your doctor about anything you think might be unusual.

During perimenopause (the years leading up to menopause), your hormone levels change. This can make your periods unpredictable and often heavier than normal. Hormone therapy ( estrogen, progesterone, or a combination of both) can help make your cycle more regular, but be sure to talk about the risks and benefits with your doctor.

This medication helps prevent blood clots, The biggest issue linked to it is bleeding. If you take this and your menstrual flow is extremely heavy or you bleed in between your periods, it’s important to let your doctor know. Aspirin also can help prevent blood clots,

1. That’s why doctors sometimes prescribe it after a heart attack or stroke, which can happen if a blood vessel becomes blocked by a clot.
2. But if you take aspirin regularly, you may notice that your periods are heavier or longer than usual.
3. If you have more bleeding than normal, talk to your doctor.
4. Other painkillers known as nonsteroidal anti-inflammatory drugs ( NSAIDs ), which include ibuprofen and naproxen, have been shown to have the opposite effect.

They can make the flow lighter during your period. Your thyroid is a gland that makes certain hormones. If it doesn’t make enough – a condition called hypothyroidism – your periods can be irregular. One drug people take to treat hypothyroidism is called levothyroxine (Levoxyl, Synthroid ).

1. It replaces the hormones normally made by your thyroid, and it can cause changes in your period.
2. Talk to your doctor if the changes cause problems for you or don’t go away.
3. Researchers have found that some women who take antidepressants have menstrual disorders like painful cramps, heavy bleeding, or missed periods as side effects.

You’re most likely to notice unusual periods in the first 3 months after you start the medication, but talk to your doctor if they don’t get back to normal after that. If your premenstrual symptoms are so serious that they affect your daily life – a condition called premenstrual dysphoric disorder (PMDD) – antidepressants may actually help.

• Studies of women who have epilepsy and take anti-epilepsy drugs have shown that many have missed or irregular periods or changes in the length of their cycles.
• Tell your doctor if you have those kinds of side effects; they may want to make sure you don’t have a condition such as polycystic ovarian syndrome, especially if you want to get pregnant,

This cancer treatment can throw your cycle out of whack and make your periods irregular or your flow heavier. Sometimes your periods may stop altogether. If you’re under age 40, they’ll probably start again after you finish treatment.

How often can you take period pain tablets?

My Account Area – 1. Name of the medicinal product Panadol Extra Advance 500 mg/65 mg Tablets Panadol Period Pain 500 mg/65 mg Tablets 2. Qualitative and quantitative composition Each tablet contains Paracetamol 500 mg and Caffeine 65 mg. For full list of excipients, see section 6.1.3. Pharmaceutical form Tablet. White to off-white, film coated, oval shaped tablets. “xPx” (with the P inside in a circle) debossed on one side, “- -” on the other side.4. Clinical particulars 4.1 Therapeutic indications A mild analgesic and antipyretic formulated to give extra pain relief. The tablets are recommended for the treatment of most painful and febrile conditions, for example, headache, including migraine, backache, toothache, rheumatic pain and dysmenorrhoea, and the relief of the symptoms of colds, influenza and sore throat.4.2 Posology and method of administration Oral use. Adults (including the elderly), and children aged 16 years and over: Two tablets up to four times daily. The dose should not be repeated more frequently than every 4 hours. Do not exceed 8 tablets in 24 hours. Children aged 12-15 years: One tablet up to four times daily. The dose should not be repeated more frequently than every 4 hours. Do not exceed 4 tablets in 24 hours. Not recommended for children under 12 years.4.3 Contraindications Hypersensitivity to paracetamol, caffeine or any of the other constituents.4.4 Special warnings and precautions for use Do not exceed stated dose. Contains paracetamol. Do not use with any other paracetamol containing products. The concomitant use with other products containing paracetamol may lead to an overdose. Paracetamol overdose may cause liver failure which may require liver transplant or lead to death. Care is advised in the administration of paracetamol to patients with renal or hepatic impairment. The hazard of overdose is greater in those with non- cirrhotic alcoholic liver disease. Caution should be exercised in patients with glutathione depleted states, as the use of paracetamol may increase the risk of metabolic acidosis (see section 4.9). Excessive intake of caffeine (e.g. coffee, tea and some canned drinks) should be avoided while taking this product. If symptoms persist, medical advice must be sought. Keep out of the sight and reach of children. Pack Label: Talk to a doctor at once if you take too much of this medicine, even if you feel well. Do not take anything else containing paracetamol while taking this medicine. Patient Information Leaflet: Talk to a doctor at once if you take too much of this medicine even if you feel well. This is because too much paracetamol can cause delayed, serious liver damage.4.5 Interaction with other medicinal products and other forms of interaction The speed of absorption of paracetamol may be increased by metoclopramide or domperidone and absorption reduced by colestyramine. The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular daily use of paracetamol with increased risk of bleeding; occasional doses have no significant effect. Caffeine may increase clearance of lithium. Concomitant use is therefore not recommended.4.6 Fertility, pregnancy and lactation Paracetamol-caffeine is not recommended for use during pregnancy due to the possible increased risk of lower birth weight and spontaneous abortion associated with caffeine consumption. Caffeine in breast milk may potentially have a stimulating effect on breast fed infants. Due to the caffeine content of this product it should not be used if you are pregnant or breast feeding.4.7 Effects on ability to drive and use machines None.4.8 Undesirable effects Adverse events from historical clinical trial data are both infrequent and from small patient exposure. Accordingly, events reported from extensive post- marketing experience at therapeutic/labelled dose and considered attributable are tabulated below by MedDRA System Organ Class. Adverse reactions identified during post-marketing use are reported voluntarily from a population of uncertain size, the frequency of these reactions is unknown but likely to be very rare (<1/10,000). Post marketing data PARACETAMOL

Body System	Undesirable effect
Blood and lymphatic system disorders	Thrombocytopenia Agranulocytosis
Immune system disorders	Very rare cases of serious skin reactions have been reported. Anaphylaxis Cutaneous hypersensitivity reactions including (amongst others) skin rashes and angioedema.
Respiratory, thoracic and mediastinal disorders	Bronchospasm- more likely in patients sensitive to aspirin and other NSAIDs
Hepatobiliary disorders	Hepatic dysfunction

CAFFEINE When the recommended paracetamol-caffeine dosing regimen is combined with dietary caffeine intake, the resulting higher dose of caffeine may increase the potential for caffeine-related adverse effects.

Body System	Undesirable effect
Central nervous system	Dizziness Headache
Cardiac disorders	Palpitation
Psychiatric disorders	Insomnia Restlessness Anxiety and irritability
Gastrointestinal disorders	Gastrointestinal disturbances

Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App store.4.9 Overdose Liver damage is possible in adults who have taken 10g or more of paracetamol.

Ingestion of 5g or more of paracetamol may lead to liver damage if the patient has risk factors (see below). Risk factors If the patient a) Is on long term treatment with carbamazepine, phenobarbitone, phenytoin, primidone, rifampicin, St John’s Wort or other drugs that induce liver enzymes. Or b) Regularly consumes ethanol in excess of recommended amounts.

Or c) Is likely to be glutathione deplete e.g. eating disorders, cystic fibrosis, HIV infection, starvation, cachexia. Symptoms Symptoms of paracetamol overdosage in the first 24 hours are pallor, nausea, vomiting, anorexia and abdominal pain. Liver damage may become apparent 12 to 48 hours after ingestion.

• Abnormalities of glucose metabolism and metabolic acidosis may occur.
• In severe poisoning, hepatic failure may progress to encephalopathy, haemorrhage, hypoglycaemia, cerebral oedema, and death.
• Acute renal failure with acute tubular necrosis, strongly suggested by loin pain, haematuria and proteinuria, may develop even in the absence of severe liver damage.

Cardiac arrhythmias and pancreatitis have been reported. Management Immediate treatment is essential in the management of paracetamol overdose. Despite a lack of significant early symptoms, patients should be referred to hospital urgently for immediate medical attention.

• Symptoms may be limited to nausea or vomiting and may not reflect the severity of overdose or the risk of organ damage.
• Management should be in accordance with established treatment guidelines, see BNF overdose section.
• Treatment with activated charcoal should be considered if the overdose has been taken within 1 hour.

Plasma paracetamol concentration should be measured at 4 hours or later after ingestion (earlier concentrations are unreliable). Treatment with N-acetylcysteine may be used up to 24 hours after ingestion of paracetamol, however, the maximum protective effect is obtained up to 8 hours post-ingestion.

• The effectiveness of the antidote declines sharply after this time.
• If required the patient should be given intravenous N- acetylcysteine, in line with the established dosage schedule.
• If vomiting is not a problem, oral methionine may be a suitable alternative for remote areas, outside hospital.
• Management of patients who present with serious hepatic dysfunction beyond 24h from ingestion should be discussed with the NPIS or a liver unit.

Caffeine Symptoms Overdose of caffeine may result in epigastric pain, vomitting, diuresis, tachycardia or cardia arrhythmia, CNS stimulation (insomnia, restlessness, excitement, agitation, jitteriness, tremors and convulsions). It must be noted that for clinically significant symptoms of caffeine overdose to occur with this product, the amount ingested would be associated with serious paracetamol-related toxicity.

Management Patients should receive general supportive care (e.g. hydration and maintenance of vital signs). The administration of activated charcoal may be beneficial when performed within one hour of the overdose, but can be considered for up to four hours after the overdose. The CNS effects of overdose may be treated with intravenous sedatives.

Summary Treatment of overdose requires assessment of plasma paracetamol levels for antidote treatment, with signs and symptoms of caffeine toxicity being managed symptomatically.5. Pharmacological properties 5.1 Pharmacodynamic properties ATC code: N02B E51 The combination of paracetamol and caffeine is a well established analgesic combination.5.2 Pharmacokinetic properties Paracetamol is rapidly and almost completely absorbed from the gastro- intestinal tract.

1. It is relatively uniformly distributed throughout most body fluids and exhibits variable protein binding.
2. Excretion is almost exclusively renal, in the form of conjugated metabolites.
3. Caffeine is absorbed readily after oral administration.
4. Maximal plasma concentrations are achieved within one hour and the plasma half-life is about 3.5 hours.65 – 80% of administered caffeine is excreted in the urine as 1-methyluric acid and 1-methylxanthine.

Panadol Extra Advance 500 mg/65 mg Tablets contain a disintegrant system which accelerates tablet dissolution compared to standard paracetamol and caffeine tablets. Human pharmacokinetic data demonstrate that the time taken to reach plasma paracetamol threshold (4-7 mcg/ml) is at least 44% faster with Panadol Extra Advance 500 mg/65 mg Tablets compared with standard paracetamol and caffeine tablets.

Total extent of absorption of paracetamol and caffeine from Panadol Extra Advance 500 mg/65 mg Tablets is equivalent to that from standard paracetamol and caffeine tablets.5.3 Preclinical safety data There are no pre-clinical data of relevance to the prescriber which are additional to that already included in other sections of the SPC.6.

Pharmaceutical particulars 6.1 List of excipients Tablet core: Starch pregelatinised, Povidone k-25, Calcium carbonate, Crospovidone, Alginic acid, Magnesium stearate, Microcrystalline cellulose. Film coat and polish: Titanium dioxide (E 171), Hypromellose, Macrogol, Polysorbate 80, Carnauba wax 6.2 Incompatibilities None.6.3 Shelf life 24 months.6.4 Special precautions for storage Store below 25°C.6.5 Nature and contents of container Tablets are in: • PVC 250 µm or 300 µm aluminium foil 30 µm blister packs in an outer cardboard carton • PVC/aluminium foil blister packs in a carboard/PVC wallet • Child resistant PVC/Aluminium foil/polyethylene terephthalate blister packs in an outer cardboard carton • Child resistant PVC/Aluminium foil/polyethylene terephthalate blister packs in a carboard/PVC wallet.

These are available in packs of, containing 4, 6, 8, 12, 14, or 16 tablets.6.6 Special precautions for disposal and other handling None.7. Marketing authorisation holder Haleon UK Trading Limited The Heights Weybridge Surrey KT13 0NY United Kingdom 8. Marketing authorisation number(s) PL 44673/0078 9.

Date of first authorisation/renewal of the authorisation First Authorisation: 26/02/2010 10. Date of revision of the text 21 st April 2023